[Austrian Syndrome: A Rare Manifestation of Invasive Pneumococcal Disease. A Case Report and Bibliographic Review]
Overview
Affiliations
The Austrian syndrome is a pathology caused by disseminated Streptococcus pneumoniae infection and characterized for the triad of pneumonia, endocarditis and meningitis. It has an estimated incidence of 0.9-7.8 cases per ten millions people each year, and a mortality of 32%. Alcohol abuse, as the main risk factor, appears only in four out of ten patients. Moreover, 14% of patientes do not have any risk factor. Two out of three patients are males and it occurs in the middle aged of life. It is more frequently on native valve, aortic valve is injured in the half of the cases. Severe regurgitation occurs in two per three patients. Appropriate antimicrobial treatment and early endocarditis surgery decrease mortality. It is possible that Austrian syndrome epidemiology is changing by the introduction of 13-valent pneumococcal conjugated vaccine in the children´s calendar.
Austrian syndrome: Resurgence of an old and deadly triad.
Rivera K, Viles D, Zielonka M, Izurieta C, Martinez T, Menendez D J Intensive Med. 2024; 4(2):261-264.
PMID: 38681791 PMC: 11043638. DOI: 10.1016/j.jointm.2023.06.006.
Austrian Syndrome: Community-Acquired Pneumonia in an Unusual Triad.
Ochoa-Diaz A, Diaz-Jurado J, Suarez-Ospino N, Silva-Martinez P, Fajardo-Rivero J Thorac Res Pract. 2023; 24(4):228-230.
PMID: 37485713 PMC: 10542100. DOI: 10.5152/ThoracResPract.2023.22113.
Meningitis and endocarditis as a sequela of streptococcus pneumonia mastoiditis: A case report.
Peebles M, Roshani M, Srivastava K Clin Case Rep. 2023; 11(7):e7648.
PMID: 37405043 PMC: 10315451. DOI: 10.1002/ccr3.7648.
Pneumococcus beyond an Austrian syndrome - A case report.
Guerreiro G, Monteiro A, Coelho L, Povoa P IDCases. 2022; 28:e01486.
PMID: 35392600 PMC: 8980754. DOI: 10.1016/j.idcr.2022.e01486.
Cardiovascular complications of bacteraemia.
de Leau M, Kuipers R BMJ Case Rep. 2021; 14(4).
PMID: 33827874 PMC: 8030674. DOI: 10.1136/bcr-2020-240341.