Pulmonary Thromboembolism Secondary to Pelvic Thrombosis Related to Giant Ovarian Tumor

Overview

Journal Autops Case Rep

Date 2019 Mar 14

PMID 30863733

Citations 3

Authors

Alberto Amadasi

Salvatore Andreola

Marta Bianchi

Michele Boracchi

Guendalina Gentile

Francesca Maciocco

Matteo Marchesi

Riccardo Zoja

Affiliations

Soon will be listed here.

Abstract

Pulmonary thromboembolism (PTE) is one of the major complications in oncologic patients. The incidence of PTE in these cases is 4 to 7 times higher than in non-oncologic patients. Ovarian tumors, specifically those of large sizes, may impair the blood flow through the pelvic veins as tumor pressure over the pelvic vessels increases the incidence of thrombosis. The authors report the case of the unexpected death of a 74-year-old female due to massive pulmonary thromboembolism, associated with an ovarian tumor almost of 15 kg of weight that filled the abdominal and pelvic cavities. The compressive effect on the walls of the pudendal and periuterine veins somehow facilitated the local thrombosis. According to the histological characterization on post-mortem samples, the mass was identified as an "atypical proliferative (borderline) mucinous tumor." The case emphasizes the important association between pulmonary thromboembolism and ovarian tumors.

Citing Articles

Giant Ovarian Tumors in Young Women: Diagnostic and Treatment Challenges-A Report of Two Cases and Narrative Review of the Recent Literature.

Melnyk M, Starczewski A, Nawrocka-Rutkowska J, Gorzko A, Melnyk B, Szydlowska I J Clin Med. 2025; 14(4).

PMID: 40004767 PMC: 11856845. DOI: 10.3390/jcm14041236.

Giant mucinous borderline ovarian tumor: challenges of diagnosis and treatment.

Sadlecki P, Dejewska K, Domieracka P, Walentowicz-Sadlecka M Arch Gynecol Obstet. 2024; .

PMID: 39441405 DOI: 10.1007/s00404-024-07793-8.

Large ovarian tumor-caused failure of VA-ECMO in a patient with cardiac arrest related to massive pulmonary embolism.

Sasajima K, Tanaka S, Kobayashi Y, Ueda T, Fukuzawa T, Aoki H J Cardiol Cases. 2023; 28(2):68-71.

PMID: 37521570 PMC: 10382969. DOI: 10.1016/j.jccase.2023.04.006.

Giant Ovarian Mucinous Borderline Tumors. A Report of Two Cases and Literature Review.

Mitragkas P, Synekidou E, Hatzimisios K Maedica (Bucur). 2022; 16(4):743-746.

PMID: 35261682 PMC: 8897801. DOI: 10.26574/maedica.2020.16.4.743.

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