Synthesis, Characterization and Antibacterial Activity of Zn(II) Coordination Polymer

In this study, the zinc(II)-based coordination polymer, [Zn(CPDA)(NO))](CPDA = 1,2-cyclopentanedicarboxylic acid) (1), had been successfully synthesized according to the hydrothermal method. Afterwards, 1 had been characterized by means of single crystal and power X-ray diffraction, elemental analysis, thermogravimetric analysis and infrared spectrum techniques. In addition, the antibacterial activities in vitro had been evaluated towards Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus), respectively, through the growth inhibition and inhibition zone experimental methods. Our results indicated that 1 had displayed favorable antibacterial activity compared with the Zinc nitrate and the CPDA ligand. These findings had revealed that the antibacterial mechanism of 1 might be correlated with the production of reactive oxygen species (ROS) in cells.