PIM1 Inhibition Effectively Enhances Plerixafor-induced HSC Mobilization by Counteracting CXCR4 Upregulation and Blocking CXCL12 Secretion

Overview

Journal Leukemia

Specialties Hematology
Oncology

Date 2019 Mar 1

PMID 30816332

Citations 4

Authors

Tony Andreas Muller

Sandra Pennisi

Anabel Zwick

Sarah Decker

Claudius Klein

Benjamin Rister

Alina Rudorf

Sandra Kissel

Marie Follo

Ralph Wasch

Anna Lena Illert

Dietmar Pfeifer

Robert Oostendorp

Claudia Waskow

Christine Dierks

Justus Duyster

Affiliations

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References

Mohle R, Bautz F, Rafii S, Moore M, Brugger W, Kanz L . The chemokine receptor CXCR-4 is expressed on CD34+ hematopoietic progenitors and leukemic cells and mediates transendothelial migration induced by stromal cell-derived factor-1. Blood. 1998; 91(12):4523-30. View