Inflammatory Dietary Pattern and Incident Psoriasis, Psoriatic Arthritis, and Atopic Dermatitis in Women: A Cohort Study

Overview

Journal J Am Acad Dermatol

Specialty Dermatology

Date 2019 Feb 25

PMID 30797850

Citations 5

Authors

Alanna C Bridgman

Abrar A Qureshi

Tricia Li

Fred K Tabung

Eunyoung Cho

Aaron M Drucker

Affiliations

Soon will be listed here.

Abstract

Background: Diet is a modulator of inflammation that might impact inflammatory skin diseases.

Objective: To assess the relationship between pro-inflammatory dietary patterns and incident psoriasis, psoriatic arthritis (PsA), and atopic dermatitis (AD).

Methods: We conducted cohort studies among women in the Nurses' Health Study II. The Empirical Dietary Inflammatory Pattern (EDIP) score was calculated at baseline and every 4 years. Incident psoriasis, PsA, and AD were assessed by validated self-report. We used multivariable-adjusted Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between EDIP quintiles and risk for psoriasis, PsA, and AD.

Results: We had 85,185 participants in the psoriasis analysis and 63,443 in the AD analysis. There were 1432 cases of psoriasis, 262 cases of PsA, and 403 cases of AD. Pro-inflammatory dietary patterns were not associated with the risk for outcomes in multivariable models (all P values for trend >.05). HRs comparing the highest to the lowest EDIP quintile were 0.99 (95% CI 0.83-1.18) for psoriasis, 1.22 (95% CI 0.81-1.83) for PsA, and 0.96 (95% CI 0.69-1.34) for AD.

Limitations: Recall and self-report.

Conclusion: Our findings do not support dietary inflammatory potential as a risk factor for psoriasis, PsA, or AD.

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