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Continuous Ictal Discharges with High Frequency Oscillations Confined to the Non-sclerotic Hippocampus in an Epileptic Patient with Radiation-induced Cavernoma in the Lateral Temporal Lobe

Overview

Overview

Journal Epilepsy Behav Case Rep

Specialty Psychology

Date 2019 Feb 23

PMID 30792954

Citations 4

Authors

Authors

Nobutaka Mukae

Takato Morioka

Michiko Torio

Ayumi Sakata

Satoshi O Suzuki

Koji Iihara

Affiliations

Affiliations

Soon will be listed here.

Abstract

Background: Intraoperative electrocorticography (iECoG) recording is recommended for treating cavernoma related epilepsy. However, "interictal" paroxysmal activities are generally recordable but are not always identical to the epileptogenic zone.

Case Description: We surgically treated a 15-year-old girl with drug-resistant epilepsy associated with radiation-induced cavernoma in the right lateral temporal lobe. iECoG revealed paroxysmal activities in the cortex around the cavernoma. Additionally, continuous subclinical "ictal" discharges with high-frequency oscillations (HFO), confined to the histologically non-sclerotic hippocampus, were recorded. Following additional hippocampectomy, a good seizure outcome was obtained.

Conclusion: iECoG and HFO analysis revealed high epileptogenicity in the non-sclerotic hippocampus of this patient.

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