Effects of -lysine·HSO Product on the Intestinal Morphology and Liver Pathology Using Broiler Model

Overview

Journal J Anim Sci Biotechnol

Publisher Biomed Central

Date 2019 Feb 19

PMID 30774948

Citations 2

Authors

Hongmin Jia

Ting He

Haitao Yu

Xiangfang Zeng

Shihai Zhang

Wenfeng Ma

Jie Zhang

Shiyan Qiao

Xi Ma

Affiliations

Soon will be listed here.

Abstract

Background: Lysine is used widely in livestock production due to the shortage of feed protein resources. -lysine·HSO contains -lysine sulphate as well as fermentation co-products which contain other amino acids and phosphorus. However, there are few articles about -lysine·HSO product regarding intestinal morphology and liver pathology of broiler chickens. In this article, we focus on the absorption and metabolism of -lysine·HSO revealed in the variation of intestinal morphology and liver pathology to determine the tolerance of chicks for -lysine·HSO.

Methods: To evaluate the tolerance of broilers for -lysine·HSO, 240 one day old broilers were allocated randomly to one of five dietary treatments which included corn-soybean diets containing 0, 1%, 4%, 7% or 10% -lysine·HSO (-lysine content = 55%).

Results: Supplementation of 1% -lysine·HSO in the diet had no negative effects. However, 4%, 7% or 10% -lysine·HSO supplementation produced negative responses on broiler performance, carcass characteristics, blood biochemistry, and particularly on intestinal morphology and liver pathology compared with broilers fed the control diet.

Conclusion: Our results show that supplementation with 1% -lysine·HSO had no negative effects on performance, carcass characteristics, blood biochemistry, intestinal morphology and liver pathology in broilers, but supplementation with 4%, 7% or 10% -lysine·HSO produced a negative response, particularly with respect to intestinal morphology and liver pathology.

Citing Articles

Impacts of Dietary Lysine and Crude Protein on Performance, Hepatic and Renal Functions, Biochemical Parameters, and Histomorphology of Small Intestine, Liver, and Kidney in Broiler Chickens.

Mousa M, Asman A, Ali R, Sayed R, Majrashi K, Fakiha K Vet Sci. 2023; 10(2).

PMID: 36851402 PMC: 9965792. DOI: 10.3390/vetsci10020098.

Tolerance and safety evaluation of sodium sulfate: A subchronic study in laying hens.

Liu B, Zhu J, Zhou Q, Yu D Anim Nutr. 2021; 7(2):576-586.

PMID: 34258447 PMC: 8245793. DOI: 10.1016/j.aninu.2020.08.009.

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