Different Light-activation Systems Associated with Dental Bleaching: a Systematic Review and a Network Meta-analysis

Overview

Journal Clin Oral Investig

Specialty Dentistry

Date 2019 Feb 16

PMID 30767069

Citations 12

Authors

Bianca Medeiros Maran

Patricia K Ziegelmann

Adrieli Burey

Thalita de Paris Matos

Alessandro D Loguercio

Alessandra Reis

Affiliations

Soon will be listed here.

Abstract

Objectives: A systematic review and a network meta-analysis were performed to answer the following research question: "Is there any light-activation protocol capable of improving color change efficacy when associated with an in-office bleaching gel in adults?"

Material And Methods: A search was performed in PubMed, Scopus, Web of Science, LILACS, BBO, Cochrane Library, and SIGLE without date and/or language restrictions in April 23, 2017 (updated on March 30, 2018). IADR abstracts (1990-2018), unpublished and ongoing trial registries, dissertations, and theses were also searched. Only randomized clinical trials conducted in adults that included at least one group treated with in-office dental bleaching with light activation were included. The risk of bias (RoB) was evaluated using the Cochrane Collaboration tool. A random-effects Bayesian-mixed treatment comparison (MTC) model was used to combine light-activated versus light-free in-office bleaching with direct light-free comparison trials. A meta-analysis with independent analysis (high- and low-concentrate hydrogen peroxide [HP]) was conducted for color change (∆E*, ∆SGU).

Results: After the removal of duplicates, title, and abstract screening, 28 studies remained. Nine were considered to be at a low RoB, five were at a high RoB, and the remaining were at an unclear RoB. The MTC analysis showed no significant difference in color change (ΔE* and ΔSGU) between light-activation protocols and light-free in-office bleaching, regardless of the HP concentration in the efficacy of the bleaching.

Conclusion: No type of light-activated in-office bleaching was superior to light-free in-office bleaching for both high- and low-concentrate in-office bleaching gels (PROSPERO-CRD42017078743).

Clinical Relevance: Although many times dental professionals use "laser whitening" as a form of marketing, this study confirmed that no type of light-activation for in-office bleaching can improve the bleaching efficacy.

Citing Articles

Effectiveness of violet LED with or without a bleaching gel: a 12-month randomized clinical trial.

Lopes A, Brondino N, Bombonatti J, Mondelli R Front Dent Med. 2025; 5:1427301.

PMID: 39917687 PMC: 11797755. DOI: 10.3389/fdmed.2024.1427301.

Tooth Sensitivity Following Hydrogen Peroxide Bleaching With and Without Ozone: A Randomized Controlled Trial: Tooth Sensitivity Following HO Versus HO/Ozone Bleaching.

Bin Hassan S Pain Res Manag. 2024; 2024:2695533.

PMID: 39512891 PMC: 11540894. DOI: 10.1155/2024/2695533.

Low and high hydrogen peroxide concentrations of in-office dental bleaching associated with violet light: an in vitro study.

Vardasca I, Favoreto M, Regis M, de Souza Carneiro T, Hul E, Borges C Clin Oral Investig. 2024; 28(3):171.

PMID: 38400920 DOI: 10.1007/s00784-024-05549-x.

Comparison of in-office and at-home bleaching techniques: An umbrella review of efficacy and post-operative sensitivity.

Aidos M, Marto C, Amaro I, Cernera M, Francisco I, Vale F Heliyon. 2024; 10(3):e25833.

PMID: 38371984 PMC: 10873745. DOI: 10.1016/j.heliyon.2024.e25833.

Treatment Durations and Whitening Outcomes of Different Tooth Whitening Systems.

Zhao X, Pan J, Malmstrom H, Ren Y Medicina (Kaunas). 2023; 59(6).

PMID: 37374334 PMC: 10302806. DOI: 10.3390/medicina59061130.

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