Recent Updates on Metabolite Composition and Medicinal Benefits of Mangosteen Plant

Overview

Journal PeerJ

Specialties Biology
Environmental Health
General Medicine

Date 2019 Feb 14

PMID 30755827

Citations 26

Authors

Wan Mohd Aizat

Ili Nadhirah Jamil

Faridda Hannim Ahmad-Hashim

Normah Mohd Noor

Affiliations

Soon will be listed here.

Abstract

Background: Mangosteen ( L.) fruit has a unique sweet-sour taste and is rich in beneficial compounds such as xanthones. Mangosteen originally been used in various folk medicines to treat diarrhea, wounds, and fever. More recently, it had been used as a major component in health supplement products for weight loss and for promoting general health. This is perhaps due to its known medicinal benefits, including as anti-oxidant and anti-inflammation. Interestingly, publications related to mangosteen have surged in recent years, suggesting its popularity and usefulness in research laboratories. However, there are still no updated reviews (up to 2018) in this booming research area, particularly on its metabolite composition and medicinal benefits.

Method: In this review, we have covered recent articles within the years of 2016 to 2018 which focus on several aspects including the latest findings on the compound composition of mangosteen fruit as well as its medicinal usages.

Result: Mangosteen has been vastly used in medicinal areas including in anti-cancer, anti-microbial, and anti-diabetes treatments. Furthermore, we have also described the benefits of mangosteen extract in protecting various human organs such as liver, skin, joint, eye, neuron, bowel, and cardiovascular tissues against disorders and diseases.

Conclusion: All in all, this review describes the numerous manipulations of mangosteen extracted compounds in medicinal areas and highlights the current trend of its research. This will be important for future directed research and may allow researchers to tackle the next big challenge in mangosteen study: drug development and human applications.

Citing Articles

Blanching-Induced Changes in Polyphenol Oxidase, Antioxidants and Phenolic Profile of Mangosteen Pericarp.

Ijod G, Nawawi N, Sulaiman R, Adzahan N, Anwar F, Azman E Food Technol Biotechnol. 2025; 62(4):465-479.

PMID: 39830870 PMC: 11740744. DOI: 10.17113/ftb.62.04.24.8513.

Medicinal plants and plant-based traditional medicine: Alternative treatments for depression and their potential mechanisms of action.

Remali J, Aizat W Heliyon. 2024; 10(20):e38986.

PMID: 39640650 PMC: 11620067. DOI: 10.1016/j.heliyon.2024.e38986.

Initial Evaluation of Safety and Immunomodulatory Potential of Dietary Supplementation with Mangosteen Pericarp Extract for Sustainable Meat Production in Native Crossbred Chickens.

Kaewtui P, Lumsangkul C, Satsook A, Sringarm K, Arjin C, Tapingkae W Life (Basel). 2024; 14(11).

PMID: 39598280 PMC: 11595714. DOI: 10.3390/life14111481.

The Effect of Sucrose and Yeast Extract on Total Phenolic, Flavonoid, and Anthocyanin of Lactic-Acid-Fermented Mangosteen Fruit Peel ( L.).

Putra K, Pradnyaswari G, Yustiantara P, Wirasuta I, Setyawan E Turk J Pharm Sci. 2024; 21(3):211-218.

PMID: 38994829 PMC: 11590547. DOI: 10.4274/tjps.galenos.2023.91267.

Influence of Different Drying Methods on Anthocyanins Composition and Antioxidant Activities of Mangosteen ( L.) Pericarps and LC-MS Analysis of the Active Extract.

Nawawi N, Ijod G, Abas F, Ramli N, Adzahan N, Azman E Foods. 2023; 12(12).

PMID: 37372562 PMC: 10297665. DOI: 10.3390/foods12122351.

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