Attenuation of ALS Progression During Pregnancy-lessons to Be Learned or Just a Coincidence?

Overview

Journal Neurol Sci

Specialty Neurology

Date 2019 Feb 13

PMID 30746559

Citations 6

Authors

Mirea Hancevic

Hrvoje Bilic

Barbara Sitas

Gordana Pavlisa

Fran Borovecki

Ivana Munitic

Ervina Bilic

Affiliations

Soon will be listed here.

Abstract

ALS is the most frequent motor neuron disorder in adults with suggested complex relationship regarding gender. Studies investigating ALS and hormones have provided varying results. ALS onset during pregnancy is uncommon and pregnancy after the ALS symptom onset is even rarer. We present three patients with the onset of ALS symptoms before or during pregnancy and propose a putative disease modifying mechanism leading to attenuation of disease progression that we observed during the pregnancies.

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