» Articles » PMID: 3072259

Conserved Sequences and Structures of Group I Introns: Building an Active Site for RNA Catalysis--a Review

Overview
Journal Gene
Specialty Molecular Biology
Date 1988 Dec 20
PMID 3072259
Citations 138
Authors
Affiliations
Soon will be listed here.
Abstract

Group I introns fold to form an active site to mediate their own RNA splicing. Sequence elements conserved among the available set of 66 group I introns are compiled. Comparative sequence analysis leads to the prediction of some conserved structural features that have not been widely appreciated. The possible significance of conserved nucleotides within base-paired duplexes is discussed; they might be involved in base triplets or alternate pairing interactions.

Citing Articles

An Actively Homing Insertion Element in a Phage Methylase Contains a Hidden HNH Endonuclease.

Arsenault D, Gosselin S, Gogarten J Genes (Basel). 2025; 16(2).

PMID: 40004507 PMC: 11855218. DOI: 10.3390/genes16020178.


The discovery of archaea: from observed anomaly to consequential restructuring of the phylogenetic tree.

Fry M Hist Philos Life Sci. 2024; 46(2):16.

PMID: 38530473 PMC: 10965645. DOI: 10.1007/s40656-024-00616-8.


Comparative mitogenome analysis reveals mitochondrial genome characteristics in eight strains of .

Bai Y, Gao X, Wang H, Ye L, Zhang X, Huang W PeerJ. 2022; 10:e14067.

PMID: 36193428 PMC: 9526403. DOI: 10.7717/peerj.14067.


Analysis of small and large subunit rDNA introns from several ectomycorrhizal fungi species.

Chen L, Yan W, Wang T, Wang Y, Liu J, Yu Z PLoS One. 2021; 16(3):e0245714.

PMID: 33720962 PMC: 7959364. DOI: 10.1371/journal.pone.0245714.


Proposal of a new nomenclature for introns in protein-coding genes in fungal mitogenomes.

Zhang S, Zhang Y IMA Fungus. 2020; 10:15.

PMID: 32647619 PMC: 7325650. DOI: 10.1186/s43008-019-0015-5.