» Articles » PMID: 30705331

A Facile Approach to Fabricate Dual Purpose Hybrid Materials for Tissue Engineering and Water Remediation

Overview
Journal Sci Rep
Specialty Science
Date 2019 Feb 2
PMID 30705331
Citations 4
Authors
Affiliations
Soon will be listed here.
Abstract

Creating hybrid materials with multifunctionality and robust mechanical stability from natural resources is a challenging proposition in materials science. Here, we report the scalable synthesis of hybrid collagen scaffolds using collagen extracted from leather industry wastes and sago starch derived from agro-industry. The hybrid scaffolds were incorporated with TiO nanoparticles and cross-linked with oxidized sago starch. The biocompatibility, thermal stability and antimicrobial property of hybrid scaffold enabled its application in burn wound healing demonstrated through albino rat models. The highly porous hybrid scaffolds are shown to be super-compressible, which is typically forbidden in materials of biological origin. We demonstrate that the hybrid scaffolds concurrently display both adsorption and absorption behavior in the removal of oil and dye molecules, respectively from contaminated water. This study paves the way for the development of novel multifunctional and shape recoverable hybrid materials specifically from renewable resources.

Citing Articles

Polysaccharide-Based Membrane Biocompatibility Study of L. and Polyvinyl Alcohol after Subcutaneous Implant in Rats.

Chagas A, de Oliveira L, Cruz M, de Melo R, Miguel M, Fernandes K Materials (Basel). 2022; 15(4).

PMID: 35207837 PMC: 8878544. DOI: 10.3390/ma15041296.


Polyurethane-Nanolignin Composite Foam Coated with Propolis as a Platform for Wound Dressing: Synthesis and Characterization.

Pahlevanneshan Z, Deypour M, Kefayat A, Rafienia M, Sajkiewicz P, Neisiany R Polymers (Basel). 2021; 13(18).

PMID: 34578092 PMC: 8473208. DOI: 10.3390/polym13183191.


Natural-Based Biomaterial for Skin Wound Healing (Gelatin vs. Collagen): Expert Review.

Naomi R, Bahari H, Ridzuan P, Othman F Polymers (Basel). 2021; 13(14).

PMID: 34301076 PMC: 8309321. DOI: 10.3390/polym13142319.


A Novel Bilayer Wound Dressing Composed of a Dense Polyurethane/Propolis Membrane and a Biodegradable Polycaprolactone/Gelatin Nanofibrous Scaffold.

Eskandarinia A, Kefayat A, Agheb M, Rafienia M, Baghbadorani M, Navid S Sci Rep. 2020; 10(1):3063.

PMID: 32080256 PMC: 7033255. DOI: 10.1038/s41598-020-59931-2.

References
1.
Ghanbari Mehrabani M, Karimian R, Rakhshaei R, Pakdel F, Eslami H, Fakhrzadeh V . Chitin/silk fibroin/TiO bio-nanocomposite as a biocompatible wound dressing bandage with strong antimicrobial activity. Int J Biol Macromol. 2018; 116:966-976. DOI: 10.1016/j.ijbiomac.2018.05.102. View

2.
Ashokkumar M, Cristian Chipara A, Tharangattu Narayanan N, Anumary A, Sruthi R, Thanikaivelan P . Three-Dimensional Porous Sponges from Collagen Biowastes. ACS Appl Mater Interfaces. 2016; 8(23):14836-44. DOI: 10.1021/acsami.6b04582. View

3.
Perumal S, Ramadass S, Madhan B . Sol-gel processed mupirocin silica microspheres loaded collagen scaffold: a synergistic bio-composite for wound healing. Eur J Pharm Sci. 2014; 52:26-33. DOI: 10.1016/j.ejps.2013.10.006. View

4.
Jithendra P, Rajam A, Kalaivani T, Mandal A, Rose C . Preparation and characterization of aloe vera blended collagen-chitosan composite scaffold for tissue engineering applications. ACS Appl Mater Interfaces. 2013; 5(15):7291-8. DOI: 10.1021/am401637c. View

5.
Seisenbaeva G, Fromell K, Vinogradov V, Terekhov A, Pakhomov A, Nilsson B . Dispersion of TiO nanoparticles improves burn wound healing and tissue regeneration through specific interaction with blood serum proteins. Sci Rep. 2017; 7(1):15448. PMC: 5684224. DOI: 10.1038/s41598-017-15792-w. View