» Articles » PMID: 30703774

Hypogonadism in Children with a Previous History of Cancer: Endocrine Management and Follow-Up

Overview
Publisher Karger
Date 2019 Feb 1
PMID 30703774
Citations 7
Authors
Affiliations
Soon will be listed here.
Abstract

Hypogonadism after treatment for childhood cancer is a recognized complication and its cause may be subdivided into primary gonadal failure and central hypogonadism. Here, we provide an overview of the risk factors for the development of hypogonadism, assessment and potential interventions and give a summary of the current recommendations for management and follow-up of hypogonadism in childhood cancer survivors.

Citing Articles

Causality between Sex Hormones and Bone Mineral Density in Childhood: Age- and Tanner-Stage-Matched Sex Hormone Level May Be an Early Indicator of Pediatric Bone Fragility.

Kim S, Kim S, Kim S, Cho W, Cho K, Jung M Biomedicines. 2024; 12(6).

PMID: 38927380 PMC: 11200954. DOI: 10.3390/biomedicines12061173.


Late Complications in Long-Term Childhood Cancer Survivors: What the Oral Health Professional Needs to Know.

Al-Ansari S, Stolze J, Bresters D, Brook A, Laheij A, Brand H Dent J (Basel). 2024; 12(1).

PMID: 38275678 PMC: 10813876. DOI: 10.3390/dj12010017.


Gonadal Function in Female Adolescent and Young Adult Survivors of Childhood Cancer.

Jin H, Lee J, Park M, Park H Cancer Res Treat. 2023; 55(3):992-1000.

PMID: 36731461 PMC: 10372588. DOI: 10.4143/crt.2022.1518.


Osteoporosis in Childhood Cancer Survivors: Physiopathology, Prevention, Therapy and Future Perspectives.

Rossi F, Tortora C, Paoletta M, Marrapodi M, Argenziano M, Di Paola A Cancers (Basel). 2022; 14(18).

PMID: 36139510 PMC: 9496695. DOI: 10.3390/cancers14184349.


Long-term Follow-up Care for Childhood, Adolescent, and Young Adult Cancer Survivors.

Hudson M, Bhatia S, Casillas J, Landier W Pediatrics. 2021; 148(3).

PMID: 34462344 PMC: 9014377. DOI: 10.1542/peds.2021-053127.


References
1.
Levine J, Kelvin J, Quinn G, Gracia C . Infertility in reproductive-age female cancer survivors. Cancer. 2015; 121(10):1532-9. DOI: 10.1002/cncr.29181. View

2.
Dewailly D, Andersen C, Balen A, Broekmans F, Dilaver N, Fanchin R . The physiology and clinical utility of anti-Mullerian hormone in women. Hum Reprod Update. 2014; 20(3):370-85. DOI: 10.1093/humupd/dmt062. View

3.
Kelsey T, McConville L, Edgar A, Ungurianu A, Mitchell R, Anderson R . Follicle Stimulating Hormone is an accurate predictor of azoospermia in childhood cancer survivors. PLoS One. 2017; 12(7):e0181377. PMC: 5519149. DOI: 10.1371/journal.pone.0181377. View

4.
Wallace W, Thomson A, Saran F, Kelsey T . Predicting age of ovarian failure after radiation to a field that includes the ovaries. Int J Radiat Oncol Biol Phys. 2005; 62(3):738-44. DOI: 10.1016/j.ijrobp.2004.11.038. View

5.
Palmert M, Dunkel L . Clinical practice. Delayed puberty. N Engl J Med. 2012; 366(5):443-53. DOI: 10.1056/NEJMcp1109290. View