Genetic Variants of Serum Alpha-1-antitrypsin (Pi Types) in Bretons

Overview

Journal Hum Hered

Specialty Genetics

Date 1978 Jan 1

PMID 306958

Citations 3

Authors

R Sesboue

R Charlionet

D Vercaigne

J GUIMBRETIERE

J P Martin

Affiliations

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Abstract

The results of Pi typing on 280 Bretons from Morbihan (Southern Brittany) are reported. 6 phenotypes and 5 alleles have been found in this study. Pi M is the most frequent as in other populations. Pi S and Pi F apears as the two main variants in population genetics.

Citing Articles

Alpha1-antitrypsin deficiency. 1: epidemiology of alpha1-antitrypsin deficiency.

Luisetti M, Seersholm N Thorax. 2004; 59(2):164-9.

PMID: 14760160 PMC: 1746939. DOI: 10.1136/thorax.2003.006494.

Transmission of the PiZ allele for alpha 1-antitrypsin deficiency: population genetic considerations.

Chakraborty R, Constans J, Majumder P Hum Genet. 1982; 62(3):193-7.

PMID: 6984842 DOI: 10.1007/BF00333517.

PI (alpha 1-Antitrypsin) subtypes: frequency of PI*M4 in several populations.

Klasen E, Bos A, Simmelink H Hum Genet. 1982; 62(2):139-41.

PMID: 6984414 DOI: 10.1007/BF00282302.