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Fast and Precise Image Generation of Blood Vessels Embedded in Skin

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Journal J Biomed Opt
Date 2019 Jan 30
PMID 30693701
Citations 1
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Abstract

A software for fast rendering the visual appearance of a blood vessel located in human skin was developed based on a numerical solution of the radiative transfer equation. The user can specify geometrical properties, such as the depth and the diameter of the vessel, and physiological properties, such as the oxygen saturation of the vessel or the blood concentration in the skin. From these data, the spatially and spectrally resolved reflectance from the skin containing the blood vessel is calculated via Monte Carlo simulations, by which a two-dimensional image is generated. The short calculation time of about a second is achieved by precalculating and storing the spatially resolved reflectance for a variety of combinations of the optical and geometrical properties. This concept gives the user the opportunity to rapidly explore the influence of the physiological and geometrical properties of the investigated blood vessel on its visual appearance. The correctness of the lookup table was validated by comparison with independent Monte Carlo simulations. Rendering examples of different blood vessels in human skins are given. The current version of the software can be downloaded at https://www.ilm-ulm.de/software.

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Jia R, Tang C, Wang B J Biomed Opt. 2021; 26(9).

PMID: 34541836 PMC: 8450381. DOI: 10.1117/1.JBO.26.9.096006.

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