Memory Integration As a Challenge to the Consolidation/Reconsolidation Hypothesis: Similarities, Differences and Perspectives

Overview

Journal Front Syst Neurosci

Specialty Neurology

Date 2019 Jan 29

PMID 30687031

Citations 9

Authors

Pascale Gisquet-Verrier

David C Riccio

Affiliations

Soon will be listed here.

Abstract

We recently proposed that retrograde amnesia does not result from a disruption of the consolidation/reconsolidation processes but rather to the integration of the internal state induced by the amnesic treatment within the initial memory. Accordingly, the performance disruption induced by an amnesic agent does not result from a disruption of the memory fixation process, but from a difference in the internal state present during the learning phase (or reactivation) and at the later retention test: a case of state-dependency. In the present article, we will review similarities and differences these two competing views may have on memory processing. We will also consider the consequences the integration concept may have on the way memory is built, maintained and retrieved, as well as future research perspectives that such a new view may generate.

Citing Articles

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References

Shors T, Matzel L . Long-term potentiation: what's learning got to do with it?. Behav Brain Sci. 1999; 20(4):597-614; discussion 614-55. DOI: 10.1017/s0140525x97001593. View

Bourtchouladze R, Abel T, Berman N, Gordon R, Lapidus K, Kandel E . Different training procedures recruit either one or two critical periods for contextual memory consolidation, each of which requires protein synthesis and PKA. Learn Mem. 1999; 5(4-5):365-74. PMC: 311273. View

Sara S . Retrieval and reconsolidation: toward a neurobiology of remembering. Learn Mem. 2001; 7(2):73-84. DOI: 10.1101/lm.7.2.73. View

Nader K, Schafe G, Le Doux J . Fear memories require protein synthesis in the amygdala for reconsolidation after retrieval. Nature. 2000; 406(6797):722-6. DOI: 10.1038/35021052. View

Gold P, van Buskirk R . Facilitation of time-dependent memory processes with posttrial epinephrine injections. Behav Biol. 1975; 13(2):145-53. DOI: 10.1016/s0091-6773(75)91784-8. View

Miller R, Matzel L . Memory involves far more than 'consolidation'. Nat Rev Neurosci. 2001; 1(3):214-6. DOI: 10.1038/35044578. View

Abel T, Lattal K . Molecular mechanisms of memory acquisition, consolidation and retrieval. Curr Opin Neurobiol. 2001; 11(2):180-7. DOI: 10.1016/s0959-4388(00)00194-x. View

Mouly A, Gervais R, Holley A . Evidence for the Involvement of Rat Olfactory Bulb in Processes Supporting Long-Term Olfactory Memory. Eur J Neurosci. 1990; 2(11):978-984. DOI: 10.1111/j.1460-9568.1990.tb00010.x. View

Bouton M . Context, ambiguity, and unlearning: sources of relapse after behavioral extinction. Biol Psychiatry. 2002; 52(10):976-86. DOI: 10.1016/s0006-3223(02)01546-9. View

10.

Doyere V, Laroche S . Linear relationship between the maintenance of hippocampal long-term potentiation and retention of an associative memory. Hippocampus. 1992; 2(1):39-48. DOI: 10.1002/hipo.450020106. View

11.

Glickman S . Perseverative neural processes and consolidation of the memory trace. Psychol Bull. 1961; 58:218-33. DOI: 10.1037/h0044212. View

12.

OVERTON D . STATE-DEPENDENT OR "DISSOCIATED" LEARNING PRODUCED WITH PENTOBARBITAL. J Comp Physiol Psychol. 1964; 57:3-12. DOI: 10.1037/h0048023. View

13.

Walker M, Brakefield T, Hobson J, Stickgold R . Dissociable stages of human memory consolidation and reconsolidation. Nature. 2003; 425(6958):616-20. DOI: 10.1038/nature01930. View

14.

Maho C, Bloch V . Responses of hippocampal cells can be conditioned during paradoxical sleep. Brain Res. 1992; 581(1):115-22. DOI: 10.1016/0006-8993(92)90350-i. View

15.

Lee J, Everitt B, Thomas K . Independent cellular processes for hippocampal memory consolidation and reconsolidation. Science. 2004; 304(5672):839-43. DOI: 10.1126/science.1095760. View

16.

Dudai Y, Eisenberg M . Rites of passage of the engram: reconsolidation and the lingering consolidation hypothesis. Neuron. 2004; 44(1):93-100. DOI: 10.1016/j.neuron.2004.09.003. View

17.

Debiec J, LeDoux J . Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala. Neuroscience. 2004; 129(2):267-72. DOI: 10.1016/j.neuroscience.2004.08.018. View

18.

Loftus E . Planting misinformation in the human mind: a 30-year investigation of the malleability of memory. Learn Mem. 2005; 12(4):361-6. DOI: 10.1101/lm.94705. View

19.

Tronson N, Wiseman S, Olausson P, Taylor J . Bidirectional behavioral plasticity of memory reconsolidation depends on amygdalar protein kinase A. Nat Neurosci. 2006; 9(2):167-9. DOI: 10.1038/nn1628. View

20.

Trifilieff P, Herry C, Vanhoutte P, Caboche J, Desmedt A, Riedel G . Foreground contextual fear memory consolidation requires two independent phases of hippocampal ERK/CREB activation. Learn Mem. 2006; 13(3):349-58. PMC: 1475817. DOI: 10.1101/lm.80206. View