A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
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Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.
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Sahu S, Agrawal A, Das P Cureus. 2021; 12(12):e12255.
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Gonzalez-Hernandez L, Alvarez-Zavala M, Cabrera-Silva R, Martinez-Ayala P, Amador-Lara F, Ramirez-Gonzalez A AIDS Res Ther. 2020; 17(1):52.
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Macauley P, Abu-Hishmeh M, Dumancas C, Alexander-Rajan V, Piedra-Chavez F, Nada K J Investig Med High Impact Case Rep. 2019; 7:2324709619883698.
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