Lifting the Veils on TMEM16E Function

Overview

Journal Channels (Austin)

Specialty Biochemistry

Date 2019 Jan 24

PMID 30672373

Citations 7

Authors

Anna Boccaccio

Eleonora Di Zanni

Antonella Gradogna

Joachim Scholz-Starke

Affiliations

Soon will be listed here.

Citing Articles

The allosteric mechanism leading to an open-groove lipid conductive state of the TMEM16F scramblase.

Khelashvili G, Kots E, Cheng X, Levine M, Weinstein H Commun Biol. 2022; 5(1):990.

PMID: 36123525 PMC: 9484709. DOI: 10.1038/s42003-022-03930-8.

Unraveling the Molecular Basis of the Dystrophic Process in Limb-Girdle Muscular Dystrophy LGMD-R12 by Differential Gene Expression Profiles in Diseased and Healthy Muscles.

Depuydt C, Goosens V, Janky R, DHondt A, De Bleecker J, Noppe N Cells. 2022; 11(9).

PMID: 35563815 PMC: 9104122. DOI: 10.3390/cells11091508.

Anoctamin 5 Knockout Mouse Model Recapitulates LGMD2L Muscle Pathology and Offers Insight Into in vivo Functional Deficits.

Thiruvengadam G, Sreetama S, Charton K, Hogarth M, Novak J, Suel-Petat L J Neuromuscul Dis. 2021; 8(s2):S243-S255.

PMID: 34633328 PMC: 8673513. DOI: 10.3233/JND-210720.

Autosomal Dominant ANO5-Related Disorder Associated With Myopathy and Gnathodiaphyseal Dysplasia.

Shaibani A, Khan S, Shinawi M Neurol Genet. 2021; 7(4):e612.

PMID: 34291158 PMC: 8290902. DOI: 10.1212/NXG.0000000000000612.

Prediction of Functional Consequences of Missense Mutations in ANO4 Gene.

Reichhart N, Milenkovic V, Wetzel C, Strauss O Int J Mol Sci. 2021; 22(5).

PMID: 33800471 PMC: 7962975. DOI: 10.3390/ijms22052732.

References

Mizuta K, Tsutsumi S, Inoue H, Sakamoto Y, Miyatake K, Miyawaki K . Molecular characterization of GDD1/TMEM16E, the gene product responsible for autosomal dominant gnathodiaphyseal dysplasia. Biochem Biophys Res Commun. 2007; 357(1):126-32. DOI: 10.1016/j.bbrc.2007.03.108. View

Scudieri P, Caci E, Venturini A, Sondo E, Pianigiani G, Marchetti C . Ion channel and lipid scramblase activity associated with expression of TMEM16F/ANO6 isoforms. J Physiol. 2015; 593(17):3829-48. PMC: 4575572. DOI: 10.1113/JP270691. View

Whitlock J, Yu K, Cui Y, Hartzell H . Anoctamin 5/TMEM16E facilitates muscle precursor cell fusion. J Gen Physiol. 2018; 150(11):1498-1509. PMC: 6219693. DOI: 10.1085/jgp.201812097. View

Falzone M, Malvezzi M, Lee B, Accardi A . Known structures and unknown mechanisms of TMEM16 scramblases and channels. J Gen Physiol. 2018; 150(7):933-947. PMC: 6028493. DOI: 10.1085/jgp.201711957. View

Bolduc V, Marlow G, Boycott K, Saleki K, Inoue H, Kroon J . Recessive mutations in the putative calcium-activated chloride channel Anoctamin 5 cause proximal LGMD2L and distal MMD3 muscular dystrophies. Am J Hum Genet. 2010; 86(2):213-21. PMC: 2820170. DOI: 10.1016/j.ajhg.2009.12.013. View