Asymmetries of Total Arterial Supply of Cerebral Hemispheres Do Not Exist

Overview

Journal Heliyon

Specialty Social Sciences

Date 2019 Jan 24

PMID 30671556

Citations 4

Authors

Arjun Burlakoti

Jaliya Kumaratilake

Jamie Taylor

Maciej Henneberg

Affiliations

Soon will be listed here.

Abstract

Background: Total blood supply to an organ, or its part, is proportional to its function. The aim of this project was to investigate whether there is a lateralisation of total functions of cerebral hemispheres by determining differences in the arterial blood supply to left and right cerebral hemispheres.

Methods: Diameters of right and left anterior, middle and posterior cerebral arteries were measured at specific sites and cross-sectional areas calculated in 203 adult brains (51 donated and dissected brain specimens and 152 cerebral arterial Computed Tomography Angiography and Magnetic Resonance Angiography images).

Findings: The sample size was large enough to provide a power of detecting as significant differences of 4%, but neither of the average cross-sectional areas of right anterior, middle and posterior cerebral arteries were significantly different from those of the anterior, middle and posterior cerebral arteries of the left side. Furthermore, combined areas of the three right cerebral arteries were not significantly different from combined areas of the left three arteries. This clearly indicates that the blood supply into the right cerebral hemisphere is not different from that of the left cerebral hemisphere. Therefore, there is no total functional lateralisation between the two cerebral hemispheres.

Conclusion: Brain lateralisation, frequently discussed in the literature, does not deferentially influence the total activity levels of cerebral hemispheres.

Citing Articles

Human cerebral blood supply via circulus arteriosus cerebri: A scoping review on its variations and clinical implications.

Ahmad A, Galassi F, Burlakoti A, Vaccarezza M, Papa V Heliyon. 2024; 10(12):e32648.

PMID: 38975214 PMC: 11225744. DOI: 10.1016/j.heliyon.2024.e32648.

Stability of OCT and OCTA in the Intensive Therapy Unit Setting.

Courtie E, Kale A, Hui B, Liu X, Capewell N, Bishop J Diagnostics (Basel). 2021; 11(8).

PMID: 34441449 PMC: 8394026. DOI: 10.3390/diagnostics11081516.

Unilateral Relapsing Primary Angiitis of the CNS: An Entity Suggesting Differences in the Immune Response Between the Cerebral Hemispheres.

AbdelRazek M, Hillis J, Guo Y, Martinez-Lage M, Gholipour T, Sloane J Neurol Neuroimmunol Neuroinflamm. 2021; 8(2).

PMID: 33402525 PMC: 7862090. DOI: 10.1212/NXI.0000000000000936.

Blood flow rate and wall shear stress in seven major cephalic arteries of humans.

Seymour R, Hu Q, Snelling E J Anat. 2019; 236(3):522-530.

PMID: 31710396 PMC: 7018638. DOI: 10.1111/joa.13119.

References

KONTOS H . Validity of cerebral arterial blood flow calculations from velocity measurements. Stroke. 1989; 20(1):1-3. DOI: 10.1161/01.str.20.1.1. View

Brown J, Jaffe J . Hypothesis on cerebral dominance. Neuropsychologia. 1975; 13(1):107-10. DOI: 10.1016/0028-3932(75)90054-8. View

Koppenhaver S, Hebert J, Fritz J, Parent E, Teyhen D, Magel J . Reliability of rehabilitative ultrasound imaging of the transversus abdominis and lumbar multifidus muscles. Arch Phys Med Rehabil. 2009; 90(1):87-94. DOI: 10.1016/j.apmr.2008.06.022. View

ABBIE A . The Morphology of the Fore-Brain Arteries, with Especial Reference to the Evolution of the Basal Ganglia. J Anat. 1934; 68(Pt 4):433-70. PMC: 1249001. View

HECAEN H, SAUGUET J . Cerebral dominance in left-handed subjects. Cortex. 1971; 7(1):19-48. DOI: 10.1016/s0010-9452(71)80020-5. View

Travis K, Leitner Y, Feldman H, Ben-Shachar M . Cerebellar white matter pathways are associated with reading skills in children and adolescents. Hum Brain Mapp. 2014; 36(4):1536-53. PMC: 4374012. DOI: 10.1002/hbm.22721. View

Siddiqi H, Tahir M, Lone K . Variations in cerebral arterial circle of Willis in adult Pakistani population. J Coll Physicians Surg Pak. 2013; 23(9):615-9. DOI: 09.2013/JCPSP.615619. View

Keysers C, Diekamp B, Gunturkun B . Evidence for physiological asymmetries in the intertectal connections of the pigeon (Columba livia) and their potential role in brain lateralisation. Brain Res. 2000; 852(2):406-13. DOI: 10.1016/s0006-8993(99)02192-7. View

Kong X, Mathias S, Guadalupe T, Glahn D, Franke B, Crivello F . Mapping cortical brain asymmetry in 17,141 healthy individuals worldwide via the ENIGMA Consortium. Proc Natl Acad Sci U S A. 2018; 115(22):E5154-E5163. PMC: 5984496. DOI: 10.1073/pnas.1718418115. View

10.

Benton A . The neuropsychology of facial recognition. Am Psychol. 1980; 35(2):176-86. DOI: 10.1037//0003-066x.35.2.176. View

11.

FRANKLIN M, Kraemer G, Shelton S, Baker E, Kalin N, Uno H . Gender differences in brain volume and size of corpus callosum and amygdala of rhesus monkey measured from MRI images. Brain Res. 2000; 852(2):263-7. DOI: 10.1016/s0006-8993(99)02093-4. View

12.

Corballis M . Lateralization of the human brain. Prog Brain Res. 2012; 195:103-21. DOI: 10.1016/B978-0-444-53860-4.00006-4. View

13.

Beaton A . The lateralized brain: the neuroscience and evolution of hemispheric asymmetries. Laterality. 2018; :1-4. DOI: 10.1080/1357650X.2018.1499749. View

14.

Gates A, Bradshaw J . The role of the cerebral hemispheres in music. Brain Lang. 1977; 4(3):403-31. DOI: 10.1016/0093-934x(77)90035-9. View

15.

Kamath S . Observations on the length and diameter of vessels forming the circle of Willis. J Anat. 1981; 133(Pt 3):419-23. PMC: 1167613. View

16.

Bever T, Chiarello R . Cerebral dominance in musicians and nonmusicians. Science. 1974; 185(4150):537-9. DOI: 10.1126/science.185.4150.537. View

17.

Gellman H, Botte M, Shankwiler J, Gelberman R . Arterial patterns of the deep and superficial palmar arches. Clin Orthop Relat Res. 2001; (383):41-6. DOI: 10.1097/00003086-200102000-00007. View

18.

Seymour R, Smith S, White C, Henderson D, Schwarz-Wings D . Blood flow to long bones indicates activity metabolism in mammals, reptiles and dinosaurs. Proc Biol Sci. 2011; 279(1728):451-6. PMC: 3234558. DOI: 10.1098/rspb.2011.0968. View

19.

Grady C, McIntosh A, Beig S, Craik F . An examination of the effects of stimulus type, encoding task, and functional connectivity on the role of right prefrontal cortex in recognition memory. Neuroimage. 2001; 14(3):556-71. DOI: 10.1006/nimg.2001.0865. View

20.

Burlakoti A, Kumaratilake J, Taylor J, Massy-Westropp N, Henneberg M . The cerebral basal arterial network: morphometry of inflow and outflow components. J Anat. 2017; 230(6):833-841. PMC: 5442140. DOI: 10.1111/joa.12604. View