Pancreatic B-cell Function in Relation to Diabetic Retinopathy in Asian Indian NIDDM Patients

Overview

Journal Acta Diabetol Lat

Specialty Endocrinology

Date 1988 Apr 1

PMID 3066087

Citations 4

Authors

C Snehalatha

R Mohan

V Mohan

A Ramachandran

M Viswanathan

Affiliations

Soon will be listed here.

Abstract

Pancreatic B-cell function in relation to diabetic retinopathy was studied in 195 NIDDM patients with long-standing diabetes. Background diabetic retinopathy (BDR) was present in 95 (48.7%) and proliferative retinopathy (PDR) in 17 (8.7%) of the subjects. There was no significant difference between the BDR, PDR, and non-retinopathy groups with respect to age, age at diagnosis of diabetes and HbA1 values. Mean duration of diabetes was higher in the PDR group (p less than 0.05). Serum C-peptide values showed no correlation with the presence of retinopathy or with the duration of diabetes. The C-peptide values were widely scattered in patients with BDR and PDR showing no association between pancreatic B-cell reserve and occurrence or severity of retinopathy in NIDDM patients. Thus, decreased pancreatic B-cell reserve does not appear to be a risk factor for diabetic retinopathy in NIDDM patients.

Citing Articles

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Relationship between C peptide and chronic complications in type-2 diabetes mellitus.

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