An Unusual Neurological Disorder with Abnormal Copper Metabolism

Overview

Journal J Neurol

Specialty Neurology

Date 1988 Sep 1

PMID 3065463

Citations 1

Authors

S Ono

H Kurisaki

Affiliations

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Abstract

Twin males aged 24 years showed dementia, dysarthria, gait disturbances and involuntary movements, with slightly low levels of serum copper and ceruloplasmin, and markedly low excretion of urinary copper. We propose that the unique combination of dementia, dysarthria, gait disturbances, involuntary movements and abnormalities of copper metabolism does not fit any known nosological entity and constitutes a "new" syndrome different from Wilson's and Menkes' diseases.

Citing Articles

A case control study of CSF copper, iron and manganese in Parkinson disease.

Gazzaniga G, Ferraro B, Camerlingo M, Casto L, Viscardi M, MAMOLI A Ital J Neurol Sci. 1992; 13(3):239-43.

PMID: 1624280 DOI: 10.1007/BF02224396.

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