Considering Type 1 Diabetes As a Form of Accelerated Muscle Aging

Overview

Journal Exerc Sport Sci Rev

Specialty Orthopedics

Date 2019 Jan 18

PMID 30653028

Citations 24

Authors

Cynthia M F Monaco

Molly A Gingrich

Thomas J Hawke

Affiliations

Soon will be listed here.

Abstract

Recent evidence reveals impairments to skeletal muscle health in adolescent/young adults with type 1 diabetes (T1D). Interestingly, the observed changes in T1D are not unlike aged muscle, particularly, the alterations to mitochondria. Thus, we put forth the novel hypothesis that T1D may be considered a condition of accelerated muscle aging and that, similar to aging, mitochondrial dysfunction is a primary contributor to this complication.

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