Mapping of Quantitative Trait Loci for Life History Traits Segregating Within Common Frog Populations

Overview

Journal Heredity (Edinb)

Specialty Genetics

Date 2019 Jan 12

PMID 30631147

Citations 3

Authors

Gemma Palomar

Anti Vasemagi

Freed Ahmad

Alfredo G Nicieza

Jose Manuel Cano

Affiliations

Soon will be listed here.

Abstract

The evolution of complex traits is often shaped by adaptive divergence. However, very little is known about the number, effect size, and location of the genomic regions influencing the variation of these traits in natural populations. Based on a dense linkage map of the common frog, Rana temporaria, we have localized, for the first time in amphibians, three significant and nine suggestive quantitative trait loci (QTLs) for metabolic rate, growth rate, development time, and weight at metamorphosis, explaining 5.6-18.9% of the overall phenotypic variation in each trait. We also found a potential pleiotropic QTL between development time and size at metamorphosis that, if confirmed, might underlie the previously reported genetic correlation between these traits. Furthermore, we demonstrate that the genetic variation linked to fitness-related larval traits segregates within Rana temporaria populations. This study provides the first insight into the genomic regions that affect larval life history traits in anurans, providing a valuable resource to delve further into the genomic basis of evolutionary change in amphibians.

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