The Involvement of Mitochondrial Fission in Maintenance of the Stemness of Bone Marrow Mesenchymal Stem Cells

Overview

Journal Exp Biol Med (Maywood)

Specialty Biology

Date 2019 Jan 8

PMID 30614257

Citations 8

Authors

Xiaorong Feng

Wenjing Zhang

Wen Yin

Y James Kang

Affiliations

Soon will be listed here.

Abstract

How to maintain the stemness of bone marrow mesenchymal stem cells (BMSCs) in cultures is a long-standing question. The present study found that mitochondrial dynamics affects the stemness of BMSCs in cultures and the retaining of mitochondrial fission enhances the stemness of BMSCs. This work thus provides a novel insight into strategic approaches to maintain the stemness of BMSCs in cultures in relation to the clinical application of bone-marrow stem cells.

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