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Premature Graying of Hair: Review with Updates

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Date 2019 Jan 5
PMID 30607038
Citations 15
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Abstract

Premature graying of hair (PGH) is defined as graying of hair before the age of 20 years in Caucasians and before 30 years in African American population. It can severely affect the self-esteem of an individual. The exact etiopathogenesis remains unknown, although it has been associated with premature aging disorders, atopy, and autoimmune diseases. Patients, who present with PGH, should be assessed for syndromes and metabolism diseases. Hair dyes remain the main modality of the treatment for cosmetic concerns after nutritional supplementation.

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References
1.
Beardsworth S, Kearney C, Steel S, Newman J, Purdie D . Premature greying of the hair is not associated with low bone mineral density. Osteoporos Int. 2000; 10(4):290-4. DOI: 10.1007/s001980050229. View

2.
Rees J . The melanocortin 1 receptor (MC1R): more than just red hair. Pigment Cell Res. 2000; 13(3):135-40. DOI: 10.1034/j.1600-0749.2000.130303.x. View

3.
Tobin D, Paus R . Graying: gerontobiology of the hair follicle pigmentary unit. Exp Gerontol. 2001; 36(1):29-54. DOI: 10.1016/s0531-5565(00)00210-2. View

4.
Jimbow K, Chen H, Park J, Thomas P . Increased sensitivity of melanocytes to oxidative stress and abnormal expression of tyrosinase-related protein in vitiligo. Br J Dermatol. 2001; 144(1):55-65. DOI: 10.1046/j.1365-2133.2001.03952.x. View

5.
Irie M, Asami S, Nagata S, Miyata M, Kasai H . Relationships between perceived workload, stress and oxidative DNA damage. Int Arch Occup Environ Health. 2001; 74(2):153-7. DOI: 10.1007/s004200000209. View