SOS Response Inhibitory Properties by Potential Probiotic Formulations of Bacillus Amyloliquefaciens B-1895 and Bacillus Subtilis KATMIRA1933 Obtained by Solid-State Fermentation

Overview

Journal Curr Microbiol

Specialty Microbiology

Date 2019 Jan 4

PMID 30603963

Citations 6

Authors

Evgeniya V Prazdnova

Maria S Mazanko

Anzhelica B Bren

Vladimir A Chistyakov

Richard Weeks

Michael L Chikindas

Affiliations

Soon will be listed here.

Abstract

The ability of fermentates of two potential probiotic strains, Bacillus amyloliquefaciens B-1895 and Bacillus subtilis KATMIRA1933, to lower the SOS response in bacteria was evaluated using Escherichia coli-based Lux biosensors (pRecA-lux) and the tested bacilli fermentates obtained through solid-state fermentation. The SOS response was stimulated by the addition of ciprofloxacine. Preparations of both Bacillus fermentates demonstrated SOS-inhibitory activity (up to 54.21%). The strain КATMIRA1933 was characterized by higher SOS-inhibitory activity. The active components of the fermentates were stable against heating, proteinase, and RNase action.

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