Identification and Antioxidant Activity of Flavonoids Extracted from Xinjiang Jujube (.) Leaves with Ultra-High Pressure Extraction Technology

Overview

Journal Molecules

Publisher MDPI

Specialty Biology

Date 2019 Jan 2

PMID 30598032

Citations 16

Authors

Li Zhang

Pengzhan Liu

Linlin Li

Ying Huang

Yunfeng Pu

Xujie Hou

Lijun Song

Affiliations

Soon will be listed here.

Abstract

In this study, the ultra-high pressure extraction (UHPE) conditions for obtaining the maximum flavonoid yield from Xinjiang jujube (.) leaves (XJL) were optimized by response surface methodology (RSM). Box⁻Behnken design (BBD) was applied to evaluate the effects of four variables (extraction temperature, pressure, time and liquid-to-solid ratio) on flavonoid yield. The results showed that the optimal flavonoid yield (25.45 ± 0.21 mg/g) was derived at 50.0 °C, 342.39 MPa, 11.56 min, and a liquid-to-solid ratio of 43.95 mL/g. Eight compounds were tentatively identified and quantified as kaempferol and quercetin glycosides with UPLC-ESI-MS. Compared to ultrasound-assisted extraction (UAE), UHPE can obtain higher concentrations of total flavonoids and stronger DPPH and ABTS radical-scavenging activities in a much shorter time. Therefore, UHPE is an alternative to UAE for obtaining flavonoids from XJL, which may be an optional method for large-scale industrial flavonoid extraction from XJL.

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