Transcriptome Protection by the Expanded Family of HnRNPs

Overview

Journal RNA Biol

Specialty Molecular Biology

Date 2019 Jan 1

PMID 30596342

Citations 9

Authors

Urmi Das

Hai Nguyen

Jiuyong Xie

Affiliations

Soon will be listed here.

Abstract

The family of heterogeneous ribonucleoproteins (hnRNPs) have multiple functions in RNA metabolism. In recent years, several hnRNPs have also been shown to be essential for the maintenance of transcriptome integrity, by preventing intronic cryptic splicing signals from mis-splicing of many endogeneous pre-mRNA transcripts. Here we discuss the possibility for a general role of this family of proteins and their expansion in transcriptome protection.

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