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A Benchmarking Between Deep Learning, Support Vector Machine and Bayesian Threshold Best Linear Unbiased Prediction for Predicting Ordinal Traits in Plant Breeding

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Journal G3 (Bethesda)
Date 2018 Dec 30
PMID 30593512
Citations 46
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Abstract

Genomic selection is revolutionizing plant breeding. However, still lacking are better statistical models for ordinal phenotypes to improve the accuracy of the selection of candidate genotypes. For this reason, in this paper we explore the genomic based prediction performance of two popular machine learning methods: the Multi Layer Perceptron (MLP) and support vector machine (SVM) methods the Bayesian threshold genomic best linear unbiased prediction (TGBLUP) model. We used the percentage of cases correctly classified (PCCC) as a metric to measure the prediction performance, and seven real data sets to evaluate the prediction accuracy, and found that the best predictions (in four out of the seven data sets) in terms of PCCC occurred under the TGLBUP model, while the worst occurred under the SVM method. Also, in general we found no statistical differences between using 1, 2 and 3 layers under the MLP models, which means that many times the conventional neuronal network model with only one layer is enough. However, although even that the TGBLUP model was better, we found that the predictions of MLP and SVM were very competitive with the advantage that the SVM was the most efficient in terms of the computational time required.

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References
1.
Money D, Gardner K, Migicovsky Z, Schwaninger H, Zhong G, Myles S . LinkImpute: Fast and Accurate Genotype Imputation for Nonmodel Organisms. G3 (Bethesda). 2015; 5(11):2383-90. PMC: 4632058. DOI: 10.1534/g3.115.021667. View

2.
Bellot P, de Los Campos G, Perez-Enciso M . Can Deep Learning Improve Genomic Prediction of Complex Human Traits?. Genetics. 2018; 210(3):809-819. PMC: 6218236. DOI: 10.1534/genetics.118.301298. View

3.
Alipanahi B, Delong A, Weirauch M, Frey B . Predicting the sequence specificities of DNA- and RNA-binding proteins by deep learning. Nat Biotechnol. 2015; 33(8):831-8. DOI: 10.1038/nbt.3300. View

4.
Nakaya A, Isobe S . Will genomic selection be a practical method for plant breeding?. Ann Bot. 2012; 110(6):1303-16. PMC: 3478044. DOI: 10.1093/aob/mcs109. View

5.
Glaubitz J, Casstevens T, Lu F, Harriman J, Elshire R, Sun Q . TASSEL-GBS: a high capacity genotyping by sequencing analysis pipeline. PLoS One. 2014; 9(2):e90346. PMC: 3938676. DOI: 10.1371/journal.pone.0090346. View