Spontaneous Closure of a Chronic Full Thickness Macular Hole After Failed Surgery

Overview

Journal Am J Ophthalmol Case Rep

Specialty Ophthalmology

Date 2018 Dec 25

PMID 30582073

Citations 5

Authors

Jennifer Lee

Vincent Q Nguyen

Mallika K Doss

Andrew W Eller

Affiliations

Soon will be listed here.

Abstract

Purpose: To describe an unusual case of spontaneous closure of a chronic, large, idiopathic, stage 4 macular hole after failed surgery.

Observations: A 75-year-old female presented with a history of a chronic, full thickness macular hole after failed surgery in the right eye. Two years after onset, she developed a fibrotic scar, which closed the macular hole and unexpectedly improved her vision. At her 4 year follow up exam, optical coherence tomography demonstrated a stable, closed macular hole with continued improvement in her visual acuity despite lack of surgical and medical intervention.

Conclusions And Importance: The spontaneous closure of an idiopathic full thickness macular hole is an unusual event. When it occurs, it is typically in an acute setting and is attributed to bridging retinal tissue, vitreofoveal separation, and a small diameter size. In this report, we show that a chronic, large break, that failed prior surgical intervention, can spontaneously close. The formation of an underlying fibrotic scar from type 1 neovascularization bridged the macular hole and improved her visual acuity.

Citing Articles

Macular Edema Causing Spontaneous Closure of a Macular Hole After Unsuccessful Primary Surgical Repair.

Ozkardes C, Sanders R, Brooks H, Shakarchi A J Vitreoretin Dis. 2024; :24741264241271733.

PMID: 39539831 PMC: 11556379. DOI: 10.1177/24741264241271733.

The time course of spontaneous closure of idiopathic full-thickness macular holes.

Neubauer J, Gelisken F, Ozturk T, Bartz-Schmidt K, Dimopoulos S Graefes Arch Clin Exp Ophthalmol. 2024; 262(9):2859-2865.

PMID: 38587655 PMC: 11377478. DOI: 10.1007/s00417-024-06465-2.

Spontaneous closure of idiopathic full-thickness macular hole after release of vitreomacular traction observed on spectral-domain optical coherence tomography.

Canamary Jr A, Rios L, Pinheiro F, Capelanes N, Regatieri C Saudi J Ophthalmol. 2022; 35(4):362-364.

PMID: 35814991 PMC: 9266474. DOI: 10.4103/1319-4534.347310.

Spontaneous closure of a chronic full-thickness idiopathic macular hole after Irvine-Gass syndrome resolution.

da Costa D, Braga P, Ariello L, Zacharias L BMC Ophthalmol. 2022; 22(1):132.

PMID: 35331177 PMC: 8944135. DOI: 10.1186/s12886-022-02354-6.

Spontaneous closure of a macular hole in an unusually long time after primary vitrectomy.

Grigera J, Feijoo T, Zambrano A Arq Bras Oftalmol. 2021; 85(5):524-527.

PMID: 34852051 PMC: 11826803. DOI: 10.5935/0004-2749.20220055.

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