Genetic Mutations in Linezolid-resistant Mycobacterium Avium Complex and Mycobacterium Abscessus Clinical Isolates

Overview

Journal Diagn Microbiol Infect Dis

Specialties Infectious Diseases
Microbiology
Pathology

Date 2018 Dec 25

PMID 30581010

Citations 7

Authors

Su-Young Kim

Byung Woo Jhun

Seong Mi Moon

Kyeongman Jeon

O Jung Kwon

Hee Jae Huh

Nam Yong Lee

Sung Jae Shin

Charles L Daley

Won-Jung Koh

Affiliations

Soon will be listed here.

Abstract

There are no studies evaluating the mechanisms driving linezolid resistance in nontuberculous mycobacteria. The novel mutations G2599A and A2137T in the 23S rRNA gene and mutations A439G and G443A in the rplD gene associated with linezolid resistance were identified in linezolid-resistant M. avium complex isolates.

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