Clinical Application of Susceptibility-weighted Imaging in the Evaluation of Leptomeningeal Collateralization

Overview

Journal Medicine (Baltimore)

Specialty General Medicine

Date 2018 Dec 22

PMID 30572437

Citations 2

Authors

Lijuan Yang

Song Luo

Affiliations

Soon will be listed here.

Abstract

The feasibility of using susceptibility-weighted imaging (SWI) in a clinical setting was assessed for quantifying leptomeningeal collateralization.Eighteen patients with stroke and acute infarction underwent diffusion-weighted imaging, SWI, perfusion-weighted imaging, and magnetic resonance angiography within 3 days after symptom onset. Lesions were evaluated by the Alberta Stroke Program Early CT score (ASPECTS), based on mean transit time, SWI, and cerebral blood volume (CBV).For evaluating ischemic penumbra and leptomeningeal collateralization, the SWI-ASPECTS significantly correlated, respectively, with mean transit time and CBV-ASPECTS (Spearman test, r = 0.793 and 0.682; P < .001, both).The SWI may be useful to quantify leptomeningeal collateralization in patients with acute cerebral infarction.

Citing Articles

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Susceptibility-diffusion mismatch correlated with leptomeningeal collateralization in large vessel occlusion stroke.

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References

Lee B, Vo K, Kido D, Mukherjee P, Reichenbach J, Lin W . MR high-resolution blood oxygenation level-dependent venography of occult (low-flow) vascular lesions. AJNR Am J Neuroradiol. 1999; 20(7):1239-42. PMC: 7055982. View

Barber P, Demchuk A, Zhang J, Buchan A . Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy. ASPECTS Study Group. Alberta Stroke Programme Early CT Score. Lancet. 2000; 355(9216):1670-4. DOI: 10.1016/s0140-6736(00)02237-6. View

Tamura H, Hatazawa J, Toyoshima H, Shimosegawa E, Okudera T . Detection of deoxygenation-related signal change in acute ischemic stroke patients by T2*-weighted magnetic resonance imaging. Stroke. 2002; 33(4):967-71. DOI: 10.1161/01.str.0000013672.70986.e2. View

Liebeskind D . Collateral circulation. Stroke. 2003; 34(9):2279-84. DOI: 10.1161/01.STR.0000086465.41263.06. View

Cho Z, Ro Y, Lim T . NMR venography using the susceptibility effect produced by deoxyhemoglobin. Magn Reson Med. 1992; 28(1):25-38. DOI: 10.1002/mrm.1910280104. View

Brozici M, van der Zwan A, Hillen B . Anatomy and functionality of leptomeningeal anastomoses: a review. Stroke. 2003; 34(11):2750-62. DOI: 10.1161/01.STR.0000095791.85737.65. View

Hendrikse J, van Raamt A, van der Graaf Y, Mali W, van der Grond J . Distribution of cerebral blood flow in the circle of Willis. Radiology. 2005; 235(1):184-9. DOI: 10.1148/radiol.2351031799. View

Ribo M, Molina C, Montaner J, Rubiera M, Delgado-Mederos R, Arenillas J . Acute hyperglycemia state is associated with lower tPA-induced recanalization rates in stroke patients. Stroke. 2005; 36(8):1705-9. DOI: 10.1161/01.STR.0000173161.05453.90.9f. View

Saqqur M, Uchino K, Demchuk A, Molina C, Garami Z, Calleja S . Site of arterial occlusion identified by transcranial Doppler predicts the response to intravenous thrombolysis for stroke. Stroke. 2007; 38(3):948-54. DOI: 10.1161/01.STR.0000257304.21967.ba. View

10.

Bang O, Saver J, Buck B, Alger J, Starkman S, Ovbiagele B . Impact of collateral flow on tissue fate in acute ischaemic stroke. J Neurol Neurosurg Psychiatry. 2007; 79(6):625-9. PMC: 2702489. DOI: 10.1136/jnnp.2007.132100. View

11.

Liebeskind D . Of mice and men: essential considerations in the translation of collateral therapeutics. Stroke. 2008; 39(12):e187-8. PMC: 2743518. DOI: 10.1161/STROKEAHA.108.522888. View

12.

Santhosh K, Kesavadas C, Thomas B, Gupta A, Thamburaj K, Kapilamoorthy T . Susceptibility weighted imaging: a new tool in magnetic resonance imaging of stroke. Clin Radiol. 2008; 64(1):74-83. DOI: 10.1016/j.crad.2008.04.022. View

13.

Lansberg M, Bluhmki E, Thijs V . Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis. Stroke. 2009; 40(7):2438-41. PMC: 2725521. DOI: 10.1161/STROKEAHA.109.552547. View

14.

Miteff F, Levi C, Bateman G, Spratt N, McElduff P, Parsons M . The independent predictive utility of computed tomography angiographic collateral status in acute ischaemic stroke. Brain. 2009; 132(Pt 8):2231-8. DOI: 10.1093/brain/awp155. View

15.

Tsui Y, Tsai F, Hasso A, Greensite F, Nguyen B . Susceptibility-weighted imaging for differential diagnosis of cerebral vascular pathology: a pictorial review. J Neurol Sci. 2009; 287(1-2):7-16. DOI: 10.1016/j.jns.2009.08.064. View

16.

Hussein H, Georgiadis A, Vazquez G, Miley J, Memon M, Mohammad Y . Occurrence and predictors of futile recanalization following endovascular treatment among patients with acute ischemic stroke: a multicenter study. AJNR Am J Neuroradiol. 2010; 31(3):454-8. PMC: 7963981. DOI: 10.3174/ajnr.A2006. View

17.

Zhang H, Prabhakar P, Sealock R, Faber J . Wide genetic variation in the native pial collateral circulation is a major determinant of variation in severity of stroke. J Cereb Blood Flow Metab. 2010; 30(5):923-34. PMC: 2949178. DOI: 10.1038/jcbfm.2010.10. View

18.

Shuaib A, Butcher K, Mohammad A, Saqqur M, Liebeskind D . Collateral blood vessels in acute ischaemic stroke: a potential therapeutic target. Lancet Neurol. 2011; 10(10):909-21. DOI: 10.1016/S1474-4422(11)70195-8. View

19.

McVerry F, Liebeskind D, Muir K . Systematic review of methods for assessing leptomeningeal collateral flow. AJNR Am J Neuroradiol. 2011; 33(3):576-82. PMC: 7966447. DOI: 10.3174/ajnr.A2794. View

20.

Huang P, Chen C, Lin W, Lin R, Khor G, Liu C . Clinical applications of susceptibility weighted imaging in patients with major stroke. J Neurol. 2011; 259(7):1426-32. DOI: 10.1007/s00415-011-6369-2. View