Antimicrobial Susceptibility and Molecular Typing of Pasteurella Multocida Isolated from Six Provinces in China

Overview

Journal Trop Anim Health Prod

Publisher Springer

Specialties Tropical Medicine
Veterinary Medicine

Date 2018 Dec 12

PMID 30535896

Citations 7

Authors

Ling-Cong Kong

Zi Wang

Yi-Ming Wang

Wen-Long Dong

Bo-Yan Jia

Duo Gao

Xiu-Yun Jiang

Hong-Xia Ma

Affiliations

Soon will be listed here.

Abstract

Pasteurella multocida (P. multocida) is an important pathogen that causes bovine respiratory disease (BRD) in China and other countries. To investigate the antimicrobial susceptibility of P. multocida isolated from different provinces in China, we analyzed antimicrobial susceptibility phenotypes and pulsed-field gel electrophoresis (PFGE) types of P. multocida; then, we sequenced the complete genome of strain found to be multidrug-resistant. The isolates exhibited resistance to many antimicrobial agents, especially amikacin, sulfamethoxazole, sulfachloropyridazinesodium, macrolides, and fluoroquinolones. Pulsed-field gel electrophoresis analysis showed that a clonal spread of multidrug-resistant isolates occurred in various provinces. All of the isolates carried class I integron.

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