Regional Anesthesia to Ameliorate Postoperative Analgesia Outcomes in Pediatric Surgical Patients: an Updated Systematic Review of Randomized Controlled Trials

Overview

Journal Local Reg Anesth

Publisher Dove Medical Press

Date 2018 Dec 12

PMID 30532585

Citations 9

Authors

Mark C Kendall

Lucas J Castro Alves

Edward I Suh

Zachary L McCormick

Gildasio S De Oliveira

Affiliations

Soon will be listed here.

Abstract

Regional anesthesia is becoming increasingly popular among anesthesiologists in the management of postoperative analgesia following pediatric surgery. The main objective of this review was to systematically evaluate the last 5 years of randomized controlled trials on the role of regional anesthesia techniques in alleviating postoperative pain associated with various pediatric surgical procedures. Forty studies on 2,408 pediatric patients were evaluated. The majority of the articles published from 2013 to 2017 reported that the use of regional anesthesia minimized postoperative pain and reduced opioid consumption. Only a few surgical procedures (cholecystectomy, inguinal hernia repair, and non-laparoscopic major abdominal surgery) reported no significant difference in the postoperative pain relief compared with the standard anesthetic management. The growing number of randomized controlled trials in the pediatric literature is very promising; however, additional confirmation is needed to reinforce the use of specific regional anesthesia techniques to provide optimal postoperative pain relief for a few surgical procedures (reconstructive ear surgery, chest wall deformity, hypospadias, umbilical hernia, cleft palate repair) in pediatric patients. More randomized controlled trials are needed to establish regional anesthesia as an essential component of postoperative analgesia management in children.

Citing Articles

Back to the Future: Historic Insights and Recent Innovations in Pediatric Regional Anesthesia.

Mathew A, Kerolus K, Bitonti N, Guzman A, Moore R, Bergese S J Clin Med. 2024; 13(22).

PMID: 39597848 PMC: 11594874. DOI: 10.3390/jcm13226704.

Analgesia strategy for inguinal hernia repair in children: a systematic review and network meta-analysis of randomized clinical trials based on regional blocks.

Xue X, Zhou Y, Yu N, Yang Z Front Pediatr. 2024; 12:1417265.

PMID: 39156026 PMC: 11327816. DOI: 10.3389/fped.2024.1417265.

Anatomical Studies Evaluating Pediatric Regional Anesthesia: A Scoping Review.

Ferreira Gomes Pereira L, Carlos R, van Schoor A, Bosenberg A, Luna N, da Costa Silva R Children (Basel). 2024; 11(6).

PMID: 38929312 PMC: 11201957. DOI: 10.3390/children11060733.

Comparison of analgesic efficacy of ultrasound-guided quadratus lumborum block versus erector spinae plane block in children undergoing elective open pyeloplasty - A randomized, double-blinded, controlled study.

Ralte I, Bhoi D, Talawar P, Prasad G, Subramaniam R, Goel P J Anaesthesiol Clin Pharmacol. 2024; 40(1):127-132.

PMID: 38666165 PMC: 11042102. DOI: 10.4103/joacp.joacp_173_22.

Application of propofol-remifentanil intravenous general anesthesia combined with regional block in pediatric ophthalmic surgery.

Li M, Fei Y, Zhang X, Chen T, Li J, Sun X BMC Anesthesiol. 2024; 24(1):147.

PMID: 38632505 PMC: 11022467. DOI: 10.1186/s12871-024-02531-8.

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