Ykt6 Mediates Autophagosome-vacuole Fusion

Overview

Journal Mol Cell Oncol

Specialty Oncology

Date 2018 Dec 8

PMID 30525099

Citations 4

Authors

Levent Bas

Daniel Papinski

Claudine Kraft

Affiliations

Soon will be listed here.

Abstract

Studying the mechanism of autophagosome-vacuole fusion has proven difficult in live yeast cells. Developing a novel fusion assay, we identified Ykt6 as the missing R-SNARE (Soluble -ethylmaleimide sensitive factor attachment protein receptor) in this process and pinpoint the place of action of all four SNAREs involved. Parallel studies have confirmed our findings in other organisms.

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References

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