An Extragastrointestinal Stromal Tumor Originating from the Pancreas

Overview

Journal Case Rep Gastroenterol

Publisher Karger

Specialty Gastroenterology

Date 2018 Dec 7

PMID 30519153

Citations 2

Authors

Seong Jae Yeo

Chang Min Cho

Hyung Jun Kwon

Seung Hyun Cho

Gab Chul Kim

An Na Seo

Han Ik Bae

Affiliations

Soon will be listed here.

Abstract

Gastrointestinal stromal tumor (GIST) is the most common mesenchymal neoplasm of the gastrointestinal tract (GIT). In fewer than 5% of cases, GIST originates primarily from outside the GIT. The occurrence of GIST originating from the pancreas is rare. Sometimes, neuroendocrine tumors should be differentiated from GISTs because of their hyperenhancing nature in radiologic images. We report a case of GIST arising in the pancreas that was confirmed by surgical resection.

Citing Articles

Rare Double Primary Malignancies: A Pancreatic Gastrointestinal Stromal Tumor Mimicking as a Metastatic Lesion of Myoepithelial Carcinoma of Parotid Gland.

Marbun V, Jamtani I, Krisnuhoni E, Panigoro S Case Rep Med. 2024; 2023:8274226.

PMID: 39263044 PMC: 11390198. DOI: 10.1155/2023/8274226.

Primary Pancreatic GIST - A-Single Centre Case Series and Systematic Review of Literature.

Gupta V, Chopde A, Chaudhari V, Bal M, Shrikhande S, Bhandare M J Gastrointest Cancer. 2024; 55(2):572-583.

PMID: 38324136 DOI: 10.1007/s12029-024-01024-8.

References

Miettinen M, Lasota J . Gastrointestinal stromal tumors--definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch. 2001; 438(1):1-12. DOI: 10.1007/s004280000338. View

Park J, Kim H, Bang B, Kim S, Jeong S, Lee D . Effectiveness of contrast-enhanced harmonic endoscopic ultrasound for the evaluation of solid pancreatic masses. World J Gastroenterol. 2014; 20(2):518-24. PMC: 3923026. DOI: 10.3748/wjg.v20.i2.518. View

Pei Q, Zou X, Zhang X, Chen M, Guo Y, Luo H . Diagnostic value of EUS elastography in differentiation of benign and malignant solid pancreatic masses: a meta-analysis. Pancreatology. 2012; 12(5):402-8. DOI: 10.1016/j.pan.2012.07.013. View

Serin K, Keskin M, Gulluoglu M, Emre A . An atypically localized gastrointestinal stromal tumor: a case report of pancreas gastrointestinal stromal tumor. Ulus Cerrahi Derg. 2015; 29(1):42-4. PMC: 4379770. DOI: 10.5152/UCD.2013.11. View

Sakamoto H, Kitano M, Matsui S, Kamata K, Komaki T, Imai H . Estimation of malignant potential of GI stromal tumors by contrast-enhanced harmonic EUS (with videos). Gastrointest Endosc. 2011; 73(2):227-37. DOI: 10.1016/j.gie.2010.10.011. View

Harewood G, Wiersema M . Endosonography-guided fine needle aspiration biopsy in the evaluation of pancreatic masses. Am J Gastroenterol. 2002; 97(6):1386-91. DOI: 10.1111/j.1572-0241.2002.05777.x. View

Gotzberger M . [Contrast enhanced endosonography (CE-EUS) for the characterization of small solid pancreatic tumors]. Z Gastroenterol. 2013; 51(11):1327-8. DOI: 10.1055/s-0033-1350544. View

Fletcher C, Berman J, Corless C, Gorstein F, Lasota J, Longley B . Diagnosis of gastrointestinal stromal tumors: A consensus approach. Hum Pathol. 2002; 33(5):459-65. DOI: 10.1053/hupa.2002.123545. View

Elgeidie A, Abou El-Magd E, El-Maaty S, El-Hawary A . Pancreatic gastrointestinal stromal tumor: A case report. Int J Surg Case Rep. 2016; 29:67-70. PMC: 5099278. DOI: 10.1016/j.ijscr.2016.08.019. View

10.

Daum O, Klecka J, Ferda J, Treska V, Vanecek T, Sima R . Gastrointestinal stromal tumor of the pancreas: case report with documentation of KIT gene mutation. Virchows Arch. 2005; 446(4):470-2. DOI: 10.1007/s00428-004-1200-4. View

11.

Ando N, Goto H, Niwa Y, Hirooka Y, Ohmiya N, Nagasaka T . The diagnosis of GI stromal tumors with EUS-guided fine needle aspiration with immunohistochemical analysis. Gastrointest Endosc. 2002; 55(1):37-43. DOI: 10.1067/mge.2002.120323. View

12.

Jang S, Lee D . Contrast-enhanced endoscopic ultrasonography: advance and current status. Ultrasonography. 2014; 33(3):161-9. PMC: 4104959. DOI: 10.14366/usg.14017. View

13.

Yamashita Y, Kato J, Ueda K, Nakamura Y, Kawaji Y, Abe H . Contrast-Enhanced Endoscopic Ultrasonography for Pancreatic Tumors. Biomed Res Int. 2015; 2015:491782. PMC: 4450244. DOI: 10.1155/2015/491782. View

14.

Soufi M, Bouziane M, Massrouri R, Chad B . Pancreatic GIST with pancreas divisum: A new entity. Int J Surg Case Rep. 2012; 4(1):68-71. PMC: 3537933. DOI: 10.1016/j.ijscr.2012.09.007. View

15.

Fujita M, Itoi T, Ikeuchi N, Sofuni A, Tsuchiya T, Ishii K . Effectiveness of contrast-enhanced endoscopic ultrasound for detecting mural nodules in intraductal papillary mucinous neoplasm of the pancreas and for making therapeutic decisions. Endosc Ultrasound. 2016; 5(6):377-383. PMC: 5206826. DOI: 10.4103/2303-9027.190927. View

16.

Blay J, Bonvalot S, Casali P, Choi H, Debiec-Richter M, Dei Tos A . Consensus meeting for the management of gastrointestinal stromal tumors. Report of the GIST Consensus Conference of 20-21 March 2004, under the auspices of ESMO. Ann Oncol. 2005; 16(4):566-78. DOI: 10.1093/annonc/mdi127. View

17.

Miettinen M . Are desmoid tumors kit positive?. Am J Surg Pathol. 2001; 25(4):549-50. DOI: 10.1097/00000478-200104000-00028. View

18.

Reith J, Goldblum J, Lyles R, Weiss S . Extragastrointestinal (soft tissue) stromal tumors: an analysis of 48 cases with emphasis on histologic predictors of outcome. Mod Pathol. 2000; 13(5):577-85. DOI: 10.1038/modpathol.3880099. View

19.

Kanamori A, Hirooka Y, Itoh A, Hashimoto S, Kawashima H, Hara K . Usefulness of contrast-enhanced endoscopic ultrasonography in the differentiation between malignant and benign lymphadenopathy. Am J Gastroenterol. 2006; 101(1):45-51. DOI: 10.1111/j.1572-0241.2006.00394.x. View

20.

Tian Y, Liu H, Shi S, Xie Y, Xu Q, Zhang J . Malignant extra-gastrointestinal stromal tumor of the pancreas: report of two cases and review of the literature. World J Gastroenterol. 2014; 20(3):863-8. PMC: 3921496. DOI: 10.3748/wjg.v20.i3.863. View