Occult Tonsillar Squamous Cell Carcinoma in 2 Dogs Presenting for Treatment of Primary Oral Squamous Cell Carcinoma

Overview

Journal Can Vet J

Specialty Veterinary Medicine

Date 2018 Dec 5

PMID 30510311

Authors

Nicholas J Rancilio

Christopher M Fulkerson

Affiliations

Soon will be listed here.

Abstract

Canine non-tonsillar oral squamous cell carcinoma (OSCC) is generally regarded as locally invasive with low rates of metastasis. Two cases of canine non-tonsillar OSCC with occult tonsillar squamous cell carcinoma (TSCC) detected with tonsillar biopsies are reported. Tonsillar biopsies and detection of occult TSCC changed the therapeutic plan and may have contributed to long-term tumor control.

References

Fulton A, Nemec A, Murphy B, Kass P, Verstraete F . Risk factors associated with survival in dogs with nontonsillar oral squamous cell carcinoma 31 cases (1990-2010). J Am Vet Med Assoc. 2013; 243(5):696-702. DOI: 10.2460/javma.243.5.696. View

. Veterinary cooperative oncology group - common terminology criteria for adverse events (VCOG-CTCAE) following chemotherapy or biological antineoplastic therapy in dogs and cats v1.1. Vet Comp Oncol. 2017; 14(4):417-446. DOI: 10.1111/vco.283. View

Tuohy J, Selmic L, Worley D, Ehrhart N, Withrow S . Outcome following curative-intent surgery for oral melanoma in dogs: 70 cases (1998-2011). J Am Vet Med Assoc. 2014; 245(11):1266-73. DOI: 10.2460/javma.245.11.1266. View

Mas A, Blackwood L, Cripps P, Murphy S, De Vos J, Dervisis N . Canine tonsillar squamous cell carcinoma -- a multi-centre retrospective review of 44 clinical cases. J Small Anim Pract. 2011; 52(7):359-64. DOI: 10.1111/j.1748-5827.2011.01075.x. View

Sarowitz B, Davis G, Kim S . Outcome and prognostic factors following curative-intent surgery for oral tumours in dogs: 234 cases (2004 to 2014). J Small Anim Pract. 2017; 58(3):146-153. DOI: 10.1111/jsap.12624. View

Grier C, Mayer M . Radiation therapy of canine nontonsillar squamous cell carcinoma. Can Vet J. 2007; 48(11):1189-91. PMC: 2034434. View

Murphy S, Hayes A, Adams V, Maglennon G, Neath P, Ladlow J . Role of carboplatin in multi-modality treatment of canine tonsillar squamous cell carcinoma--a case series of five dogs. J Small Anim Pract. 2006; 47(4):216-20. DOI: 10.1111/j.1748-5827.2006.00020.x. View

Schmidt B, Glickman N, DeNicola D, de Gortari A, Knapp D . Evaluation of piroxicam for the treatment of oral squamous cell carcinoma in dogs. J Am Vet Med Assoc. 2001; 218(11):1783-6. DOI: 10.2460/javma.2001.218.1783. View

de Vos J, Burm A, Focker A, Boschloo H, Karsijns M, van der Waal I . Piroxicam and carboplatin as a combination treatment of canine oral non-tonsillar squamous cell carcinoma: a pilot study and a literature review of a canine model of human head and neck squamous cell carcinoma. Vet Comp Oncol. 2009; 3(1):16-24. DOI: 10.1111/j.1476-5810.2005.00065.x. View

10.

Boria P, Murry D, Bennett P, Glickman N, Snyder P, Merkel B . Evaluation of cisplatin combined with piroxicam for the treatment of oral malignant melanoma and oral squamous cell carcinoma in dogs. J Am Vet Med Assoc. 2004; 224(3):388-94. DOI: 10.2460/javma.2004.224.388. View

11.

Brooks M, Matus R, Leifer C, Alfieri A, Patnaik A . Chemotherapy versus chemotherapy plus radiotherapy in the treatment of tonsillar squamous cell carcinoma in the dog. J Vet Intern Med. 1988; 2(4):206-11. DOI: 10.1111/j.1939-1676.1988.tb00318.x. View

12.

BRODEY R . The biological behaviour of canine oral and pharyngeal neoplasms. J Small Anim Pract. 1970; 11(1):45-53. DOI: 10.1111/j.1748-5827.1970.tb07038.x. View

13.

Ladue T, Klein M . Toxicity criteria of the veterinary radiation therapy oncology group. Vet Radiol Ultrasound. 2001; 42(5):475-6. DOI: 10.1111/j.1740-8261.2001.tb00973.x. View

14.

Theon A, Rodriguez C, Madewell B . Analysis of prognostic factors and patterns of failure in dogs with malignant oral tumors treated with megavoltage irradiation. J Am Vet Med Assoc. 1997; 210(6):778-84. View

15.

Grant J, North S . Evaluation of the factors contributing to long-term survival in canine tonsillar squamous cell carcinoma. Aust Vet J. 2016; 94(6):197-202. DOI: 10.1111/avj.12444. View

16.

Mestrinho L, Bernardo E, Niza M, Lloret A, Buracco P . Neoadjuvant chemoradiotherapy and surgery as treatment for oral maxillary squamous cell carcinoma in a dog. Aust Vet J. 2012; 90(7):264-8. DOI: 10.1111/j.1751-0813.2012.00928.x. View