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The Role of Cognitive Rehabilitation in Limbic Encephalitis: A Case Report

Abstract

Rationale: Limbic encephalitis is a parenchymal inflammation caused by viral, bacterial, or other microbial and postinfectious agents, which is usually expressed by multifocal neurological signs and cognitive impairment.

Patient Concerns: A 50-year-old female was admitted in postacute phase, at our rehabilitative Center, to undertake neuro-motor treatment for a period of 4 months.

Diagnoses: The patient was affected by limbic encephalitis. Clinical presentation revealed attention, memory and executive dysfunctions, as well as behavioral changes, emotional dysregulation and reduction of self-awareness.

Interventions: The patients received an intensive cognitive and motor rehabilitation training.

Outcomes: Neuropsychological assessment and magnetic resonance imaging were performed before and after rehabilitative training to evaluate the cognitive and cerebral changes induced by treatment. The patient showed an improvement in cognitive performances and behavioral aspects.

Lessons: The reducing cognitive deficits, especially memory deficits, could improve quality of life by using available cognitive resources.

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References
1.
Chandra S, Seshadri R, Chikabasaviah Y, Issac T . Progressive limbic encephalopathy: Problems and prospects. Ann Indian Acad Neurol. 2014; 17(2):166-70. PMC: 4090841. DOI: 10.4103/0972-2327.132616. View

2.
Greve K, Houston R, Adams D, Stanford M, Bianchini K, Clancy A . The neurobehavioural consequences of St. Louis encephalitis infection. Brain Inj. 2002; 16(10):917-27. DOI: 10.1080/02699050210131920. View

3.
Venkatesan A, Geocadin R . Diagnosis and management of acute encephalitis: A practical approach. Neurol Clin Pract. 2014; 4(3):206-215. PMC: 4121461. DOI: 10.1212/CPJ.0000000000000036. View

4.
Kayser M, Dalmau J . Anti-NMDA Receptor Encephalitis in Psychiatry. Curr Psychiatry Rev. 2014; 7(3):189-193. PMC: 3983958. DOI: 10.2174/157340011797183184. View

5.
Hokkanen L, Launes J . Neuropsychological sequelae of acute-onset sporadic viral encephalitis. Neuropsychol Rehabil. 2007; 17(4-5):450-77. DOI: 10.1080/09602010601137039. View