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Atypical Presentation of Necrobiosis Lipoidica in a Pediatric Patient

Overview
Publisher Wiley
Specialties Dermatology
Pediatrics
Date 2018 Dec 4
PMID 30506892
Citations 3
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Abstract

Necrobiosis lipoidica (NL) is a rare chronic granulomatous inflammatory skin disease characterized by brownish-red papules and yellowish plaques with atrophic centers, which usually affect the legs, bilaterally. The average age of onset is 30-40 years, and there are very few reported cases of necrobiosis lipoidica in children. A nondiabetic girl aged 14 years presented to our clinic with a history of an asymptomatic, 7 × 5-cm single red plaque over her back in the interscapular area, which had started 5 years ago. Her laboratory tests were normal. A histopathologic evaluation confirmed the diagnosis of NL, and local treatment with clobetasol propionate twice daily was administrated. The patient will be followed up to monitor plasma glucose levels and evaluation of the lesion. Herein, we report a pediatric patient without diabetes mellitus who had NL in an atypical location and review the literature in view of the clinical features, complications, and treatment regimens for NL in children.

Citing Articles

A Breakthrough in the Treatment of Necrobiosis Lipoidica? Update on Treatment, Etiopathogenesis, Diagnosis, and Clinical Presentation.

Naumowicz M, Modzelewski S, Macko A, Luniewski B, Baran A, Flisiak I Int J Mol Sci. 2024; 25(6).

PMID: 38542454 PMC: 10970963. DOI: 10.3390/ijms25063482.


Necrobiosis Lipoidica: Atypical Presentation in a Diabetic Girl.

Alhameedy M Case Rep Dermatol. 2022; 13(3):547-552.

PMID: 35082617 PMC: 8739632. DOI: 10.1159/000520588.


Necrobiosis Lipoidica Affecting the Leg: What Is the Best Treatment in a Patient with Very High Aesthetic Demand?.

Baccarani A, De Maria F, Pappalardo M, Pedone A, De Santis G Plast Reconstr Surg Glob Open. 2020; 8(7):e3000.

PMID: 32802684 PMC: 7413758. DOI: 10.1097/GOX.0000000000003000.