Correlation Between Streptococcus Bovis Bacteremia and Density of Cows in Galicia, Northwest of Spain

Overview

Journal Infection

Date 2018 Dec 1

PMID 30498902

Citations 3

Authors

J Corredoira

E Miguez

L M Mateo

R Fernandez-Rodriguez

J F Garcia-Rodriguez

A Perez-Gonzalez

A Sanjurjo

M V Pulian

R Rabunal

Affiliations

Soon will be listed here.

Abstract

Background: There are few data on the epidemiology of infections caused by Streptococcus bovis (Sb). Some studies suggest that both residence in rural areas and contact with livestock could be potential risk factors.

Methods: We performed a retrospective study for the period 2005-2016 of all cases of bacteremia caused by Sb in Galicia (a region in the northwest of Spain). The association between the incidence rate of Sb bacteremia and the number of cattle by province and district was analyzed.

Results: 677 cases were included with a median age of 76 years, 69.3% males. The most frequent infections were endocarditis (234 cases, 34.5%), primary bacteremia (213 cases, 31.5%) and biliary infection (119 cases, 17.5%). In 252 patients, colon neoplasms were detected (37.2%). S. gallolyticus subsp. gallolyticus was the predominant species (52.3%). Mortality was 15.5% (105 cases). The annual incidence rate was 20.2 cases/10 inhabitants and was correlated with the density of cattle (p < 0.001), but not with rurality. When comparing the two provinces with a strong predominance of rural population, but with important differences in the number of cattle, such as Orense and Lugo, with 6% and 47.7% of Galician cattle, respectively, the rates were very different: 15.8 and 43.6 cases/10, respectively, with an RR of 2.7 (95% CI, 2.08-3.71). Some districts of the province of Lugo had rates higher than 100 cases/10 inhabitants.

Conclusions: Our study shows a significant correlation between the rates of Sb bacteremia and cattle density, suggesting a possible transmission of Sb from cows to people.

Citing Articles

-bacteremia: subspecies distribution and association with colorectal cancer: a retrospective cohort study.

Oberg J, Rasmussen M, Buchwald P, Nilson B, Inghammar M Epidemiol Infect. 2024; 150:e8.

PMID: 38751047 PMC: 8753481. DOI: 10.1017/S0950268821002533.

Acute Calculous Cholecystitis Caused by : A Case Report.

Shigemori T, Hiasa A, Inoue Y, Oka S, Yasuma T, Nishiwaki R Microorganisms. 2022; 10(10).

PMID: 36296204 PMC: 9610366. DOI: 10.3390/microorganisms10101929.

Disseminated infection after consumption of manatee meat: A case report and review of the literature.

Cadavid Aljure D, Posada-Velez V, Betancur Vasquez L, Villalobos J, Villa Franco J, Pereira J IDCases. 2020; 21:e00914.

PMID: 32714834 PMC: 7369581. DOI: 10.1016/j.idcr.2020.e00914.

References

Hoen B, Alla F, Selton-Suty C, Beguinot I, Bouvet A, Briancon S . Changing profile of infective endocarditis: results of a 1-year survey in France. JAMA. 2002; 288(1):75-81. DOI: 10.1001/jama.288.1.75. View

Lee R, Woo P, To A, Lau S, Wong S, Yuen K . Geographical difference of disease association in Streptococcus bovis bacteraemia. J Med Microbiol. 2003; 52(Pt 10):903-908. DOI: 10.1099/jmm.0.05199-0. View

Jean S, Teng L, Hsueh P, Ho S, Luh K . Bacteremic Streptococcus bovis infections at a university hospital, 1992-2001. J Formos Med Assoc. 2004; 103(2):118-23. View

Devriese L, Laurier L, De Herdt P, Haesebrouck F . Enterococcal and streptococcal species isolated from faeces of calves, young cattle and dairy cows. J Appl Bacteriol. 1992; 72(1):29-31. DOI: 10.1111/j.1365-2672.1992.tb04877.x. View

Hoen B, Chirouze C, Cabell C, Selton-Suty C, Duchene F, Olaison L . Emergence of endocarditis due to group D streptococci: findings derived from the merged database of the International Collaboration on Endocarditis. Eur J Clin Microbiol Infect Dis. 2005; 24(1):12-6. DOI: 10.1007/s10096-004-1266-6. View

Bordes-Benitez A, Sanchez-Onoro M, Suarez-Bordon P, Garcia-Rojas A, Saez-Nieto J, Gonzalez-Garcia A . Outbreak of Streptococcus equi subsp. zooepidemicus infections on the island of Gran Canaria associated with the consumption of inadequately pasteurized cheese. Eur J Clin Microbiol Infect Dis. 2006; 25(4):242-6. DOI: 10.1007/s10096-006-0119-x. View

Lun Z, Wang Q, Chen X, Li A, Zhu X . Streptococcus suis: an emerging zoonotic pathogen. Lancet Infect Dis. 2007; 7(3):201-9. DOI: 10.1016/S1473-3099(07)70001-4. View

Giannitsioti E, Chirouze C, Bouvet A, Beguinot I, Delahaye F, Mainardi J . Characteristics and regional variations of group D streptococcal endocarditis in France. Clin Microbiol Infect. 2007; 13(8):770-6. DOI: 10.1111/j.1469-0691.2007.01753.x. View

Corredoira J, Alonso M, Pita J, Alonso-Mesonero D . Association between rural residency, group D streptococcal endocarditis and colon cancer?. Clin Microbiol Infect. 2007; 14(2):190. DOI: 10.1111/j.1469-0691.2007.01913.x. View

10.

Beck M, Frodl R, Funke G . Comprehensive study of strains previously designated Streptococcus bovis consecutively isolated from human blood cultures and emended description of Streptococcus gallolyticus and Streptococcus infantarius subsp. coli. J Clin Microbiol. 2008; 46(9):2966-72. PMC: 2546750. DOI: 10.1128/JCM.00078-08. View

11.

Rusniok C, Couve E, Da Cunha V, El Gana R, Zidane N, Bouchier C . Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis. J Bacteriol. 2010; 192(8):2266-76. PMC: 2849448. DOI: 10.1128/JB.01659-09. View

12.

Gonzalez-Quintela A, Fernandez-Conde S, Alves M, Campos J, Lopez-Raton M, Puerta R . Temporal and spatial patterns in the rate of alcohol withdrawal syndrome in a defined community. Alcohol. 2010; 45(2):105-11. DOI: 10.1016/j.alcohol.2010.08.001. View

13.

Lin I, Liu T, Teng Y, Wu H, Liu Y, Wu K . Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence. PLoS One. 2011; 6(5):e20519. PMC: 3102119. DOI: 10.1371/journal.pone.0020519. View

14.

Vergara-Lopez S, de Alarcon A, Mateos-Gomez A, Georgieva R, Gonzalez-Nieto J, Guerrero Sanchez F . [Descriptive analysis of diseases associated with Streptococcus bovis bacteremia]. Med Clin (Barc). 2011; 137(12):527-32. DOI: 10.1016/j.medcli.2011.02.034. View

15.

Romero B, Morosini M, Loza E, Rodriguez-Banos M, Navas E, Canton R . Reidentification of Streptococcus bovis isolates causing bacteremia according to the new taxonomy criteria: still an issue?. J Clin Microbiol. 2011; 49(9):3228-33. PMC: 3165630. DOI: 10.1128/JCM.00524-11. View

16.

Boleij A, van Gelder M, Swinkels D, Tjalsma H . Clinical Importance of Streptococcus gallolyticus infection among colorectal cancer patients: systematic review and meta-analysis. Clin Infect Dis. 2011; 53(9):870-8. DOI: 10.1093/cid/cir609. View

17.

Gomez-Garces J, Gil Y, Burillo A, Wilhelmi I, Palomo M . [Diseases associated with bloodstream infections caused by the new species included in the old Streptococcus bovis group]. Enferm Infecc Microbiol Clin. 2012; 30(4):175-9. DOI: 10.1016/j.eimc.2011.09.015. View

18.

Corredoira-Sanchez J, Garcia-Garrote F, Rabunal R, Lopez-Roses L, Garcia-Pais M, Castro E . Association between bacteremia due to Streptococcus gallolyticus subsp. gallolyticus (Streptococcus bovis I) and colorectal neoplasia: a case-control study. Clin Infect Dis. 2012; 55(4):491-6. DOI: 10.1093/cid/cis434. View

19.

Coffey S, Nadarasa K, Pan A, van der Linden A, Chu J, Schultz M . The increasing incidence of Streptococcus bovis endocarditis and bacteraemia: a case series from 1997 to 2010. Int J Cardiol. 2012; 161(2):111-3. DOI: 10.1016/j.ijcard.2012.06.031. View

20.

Lazarovitch T, Shango M, Levine M, Brusovansky R, Akins R, Hayakawa K . The relationship between the new taxonomy of Streptococcus bovis and its clonality to colon cancer, endocarditis, and biliary disease. Infection. 2012; 41(2):329-37. DOI: 10.1007/s15010-012-0314-x. View