Frailty Predicts Severe Postoperative Complications After Elective Colorectal Surgery

Overview

Journal Am J Surg

Specialty General Surgery

Date 2018 Nov 27

PMID 30473227

Citations 30

Authors

Hirohisa Okabe

Takayuki Ohsaki

Katsuhiro Ogawa

Nobuyuki Ozaki

Hiromitsu Hayashi

Shinichi Akahoshi

Yoshiaki Ikuta

Kenichi Ogata

Hideo Baba

Hiroshi Takamori

Affiliations

Soon will be listed here.

Abstract

Background: We aim to clarify if frailty affects severe postoperative complications in elective colorectal surgery.

Methods: Consecutive 269 colorectal cancer patients older than 65 years undergoing curative surgery were enrolled in this study. The relevance of the frailty and sarcopenia to postoperative outcome was assessed. Clinical frailty (CF) was defined as clinical frailty scale (CFS) ≥ 4. Sarcopenia was assessed by measuring skeletal muscle area using computed tomography.

Results: Seventy-eight patients (29%) had CF and 159 patients (59%) had sarcopenia. CF was significantly associated with older age (P = 0.0008), postoperative severe complications (P = 0.001), and postoperative in-hospital stay (P < 0.0001), although sarcopenia was not. Logistic regression analysis revealed that low anterior resection and CF were independent predictors of severe postoperative complications (P = 0.038 and P = 0.001, respectively).

Conclusion: CF, but not sarcopenia, is a robust predictor of severe postoperative complications in patients with colorectal cancer.

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