Comparison of 2016-17 and Previous Epizootics of Highly Pathogenic Avian Influenza H5 Guangdong Lineage in Europe

Overview

Journal Emerg Infect Dis

Specialty Infectious Diseases

Date 2018 Nov 21

PMID 30457528

Citations 39

Authors

Pablo Alarcon

Adam Brouwer

Divya Venkatesh

Daisy Duncan

Chrysostomos I Dovas

George Georgiades

Isabella Monne

Alice Fusaro

Adam Dan

Krzysztof Smietanka

Vassilios Ragias

Andrew C Breed

Taxiarchis Chassalevris

Gabriela Goujgoulova

Charlotte Kristiane Hjulsager

Eoin Ryan

Azucena Sanchez

Eric Niqueux

Niina Tammiranta

Siamak Zohari

David A Stroud

Vladimir Savic

Nicola S Lewis

Ian H Brown

Affiliations

Soon will be listed here.

Abstract

We analyzed the highly pathogenic avian influenza (HPAI) H5 epizootic of 2016-17 in Europe by epidemiologic and genetic characteristics and compared it with 2 previous epizootics caused by the same H5 Guangdong lineage. The 2016-17 epizootic was the largest in Europe by number of countries and farms affected and greatest diversity of wild birds infected. We observed significant differences among the 3 epizootics regarding region affected, epidemic curve, seasonality, and outbreak duration, making it difficult to predict future HPAI epizootics. However, we know that in 2005-06 and 2016-17 the initial peak of wild bird detections preceded the peak of poultry outbreaks within Europe. Phylogenetic analysis of 2016-17 viruses indicates 2 main pathways into Europe. Our findings highlight the need for global surveillance of viral changes to inform disease preparedness, detection, and control.

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