Fetal Membrane Architecture, Aging and Inflammation in Pregnancy and Parturition

Overview

Journal Placenta

Publisher Elsevier

Specialties Gynecology & Obstetrics
Physiology
Reproductive Medicine

Date 2018 Nov 21

PMID 30454905

Citations 76

Authors

Ramkumar Menon

Lauren S Richardson

Martha Lappas

Affiliations

Soon will be listed here.

Abstract

Preterm birth is the single major cause of infant mortality. Short and long term outcomes for infants are often worse in cases of preterm premature rupture of the fetal membranes (pPROM). Thus, increased knowledge of the structure characteristics of fetal membranes as well as the mechanisms of membrane rupture are essential if we are to develop effective treatment strategies to prevent pPROM. In this review, we focus on the role of inflammation and senescence in fetal membrane biology.

Citing Articles

Determining Sex-Specific Gene Expression Differences in Human Chorion Trophoblast Cells.

Goncharov D, Lintao R, Urrabaz-Garza R, Radnaa E, Kammala A, Richardson L Int J Mol Sci. 2025; 26(5).

PMID: 40076861 PMC: 11900912. DOI: 10.3390/ijms26052239.

Lead exposure at the feto-maternal interface: a cause for concern for fetal membrane trophoblasts.

Flores-Espinosa P, Menon R, Kammala A, Ananth K, Richardson L, Richardson L Toxicol Sci. 2024; 203(2):195-205.

PMID: 39579145 PMC: 11775422. DOI: 10.1093/toxsci/kfae149.

Galectin-1 Elicits a Tissue-Specific Anti-Inflammatory and Anti-Degradative Effect Upon LPS-Induced Response in an Ex Vivo Model of Human Fetal Membranes Modeling an Intraamniotic Inflammation.

Hernandez-Rodriguez J, Perez-Hernandez J, Flores-Espinosa P, Olmos-Ortiz A, Velazquez P, Zamora-Escudero R Am J Reprod Immunol. 2024; 92(5):e70016.

PMID: 39575516 PMC: 11582940. DOI: 10.1111/aji.70016.

Determinants of preterm prelabor rupture of fetal membrane among pregnant women in Ethiopia: A systematic review and meta-analysis.

Geremew H, Ali M, Simegn M, Golla E, Abate A, Wondie S PLoS One. 2024; 19(11):e0311151.

PMID: 39514514 PMC: 11548779. DOI: 10.1371/journal.pone.0311151.

C/EBPδ deficiency delays infection-induced preterm birth.

Lei W, Zhang F, Li M, Pan F, Ling L, Lu J BMC Med. 2024; 22(1):432.

PMID: 39379940 PMC: 11462803. DOI: 10.1186/s12916-024-03650-2.

References

Kubo K, Ohnishi S, Hosono H, Fukai M, Kameya A, Higashi R . Human Amnion-Derived Mesenchymal Stem Cell Transplantation Ameliorates Liver Fibrosis in Rats. Transplant Direct. 2016; 1(4):e16. PMC: 4946462. DOI: 10.1097/TXD.0000000000000525. View

Malak T, Ockleford C, Bell S, Dalgleish R, Bright N, Macvicar J . Confocal immunofluorescence localization of collagen types I, III, IV, V and VI and their ultrastructural organization in term human fetal membranes. Placenta. 1993; 14(4):385-406. DOI: 10.1016/s0143-4004(05)80460-6. View

Babizhayev M, Yegorov Y . Smoking and health: association between telomere length and factors impacting on human disease, quality of life and life span in a large population-based cohort under the effect of smoking duration. Fundam Clin Pharmacol. 2010; 25(4):425-42. DOI: 10.1111/j.1472-8206.2010.00866.x. View

Fox H, Faulk W . The placenta as an experimental model. Clin Endocrinol Metab. 1981; 10(1):57-72. DOI: 10.1016/s0300-595x(81)80038-2. View

Lim R, Barker G, Lappas M . Inhibition of PIM1 kinase attenuates inflammation-induced pro-labour mediators in human foetal membranes in vitro. Mol Hum Reprod. 2017; 23(6):428-440. DOI: 10.1093/molehr/gax013. View

Ilmonen P, Kotrschal A, Penn D . Telomere attrition due to infection. PLoS One. 2008; 3(5):e2143. PMC: 2366059. DOI: 10.1371/journal.pone.0002143. View

MOSSMAN H . Classics revisited: Comparative morphogenesis of the fetal membranes and accessory uterine structures. Placenta. 1991; 12(1):1-5. DOI: 10.1016/0143-4004(91)90504-9. View

Menon R, Boldogh I, Urrabaz-Garza R, Polettini J, Syed T, Saade G . Senescence of primary amniotic cells via oxidative DNA damage. PLoS One. 2014; 8(12):e83416. PMC: 3873937. DOI: 10.1371/journal.pone.0083416. View

Faulk W, Matthews R, Stevens P, Bennett J, Burgos H, Hsi B . Human amnion as an adjunct in wound healing. Lancet. 1980; 1(8179):1156-8. DOI: 10.1016/s0140-6736(80)91617-7. View

10.

Watson A . The cell biology of blastocyst development. Mol Reprod Dev. 1992; 33(4):492-504. DOI: 10.1002/mrd.1080330417. View

11.

Menon R, Richardson L . Preterm prelabor rupture of the membranes: A disease of the fetal membranes. Semin Perinatol. 2017; 41(7):409-419. PMC: 5659934. DOI: 10.1053/j.semperi.2017.07.012. View

12.

Coppe J, Desprez P, Krtolica A, Campisi J . The senescence-associated secretory phenotype: the dark side of tumor suppression. Annu Rev Pathol. 2010; 5:99-118. PMC: 4166495. DOI: 10.1146/annurev-pathol-121808-102144. View

13.

Sheller-Miller S, Urrabaz-Garza R, Saade G, Menon R . Damage-Associated molecular pattern markers HMGB1 and cell-Free fetal telomere fragments in oxidative-Stressed amnion epithelial cell-Derived exosomes. J Reprod Immunol. 2017; 123:3-11. PMC: 5632595. DOI: 10.1016/j.jri.2017.08.003. View

14.

Lim R, Barker G, Wall C, Lappas M . Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium. Mol Hum Reprod. 2013; 19(7):451-62. DOI: 10.1093/molehr/gat015. View

15.

Dutta E, Behnia F, Boldogh I, Saade G, Taylor B, Kacerovsky M . Oxidative stress damage-associated molecular signaling pathways differentiate spontaneous preterm birth and preterm premature rupture of the membranes. Mol Hum Reprod. 2015; 22(2):143-57. DOI: 10.1093/molehr/gav074. View

16.

Strauss 3rd J . Extracellular matrix dynamics and fetal membrane rupture. Reprod Sci. 2012; 20(2):140-53. PMC: 3826277. DOI: 10.1177/1933719111424454. View

17.

Miki T . Amnion-derived stem cells: in quest of clinical applications. Stem Cell Res Ther. 2011; 2(3):25. PMC: 3152995. DOI: 10.1186/scrt66. View

18.

Sukhikh G, Kan N, Tyutyunnik V, Sannikova M, Dubova E, Pavlov K . The role of extracellular inducer of matrix metalloproteinases in premature rupture of membranes. J Matern Fetal Neonatal Med. 2015; 29(4):656-9. DOI: 10.3109/14767058.2015.1015416. View

19.

Menon R, Boldogh I, Hawkins H, Woodson M, Polettini J, Syed T . Histological evidence of oxidative stress and premature senescence in preterm premature rupture of the human fetal membranes recapitulated in vitro. Am J Pathol. 2014; 184(6):1740-51. DOI: 10.1016/j.ajpath.2014.02.011. View

20.

Dixon C, Richardson L, Sheller-Miller S, Saade G, Menon R . A distinct mechanism of senescence activation in amnion epithelial cells by infection, inflammation, and oxidative stress. Am J Reprod Immunol. 2017; 79(3). PMC: 5815890. DOI: 10.1111/aji.12790. View