» Articles » PMID: 30446985

SEOM Clinical Guidelines for the Treatment of Non-small Cell Lung Cancer (2018)

Overview
Specialty Oncology
Date 2018 Nov 18
PMID 30446985
Citations 69
Authors
Affiliations
Soon will be listed here.
Abstract

Non-small cell lung cancer (NSCLC) accounts for up to 85% of all lung cancers. The last few years have seen the development of a new staging system, diagnostic procedures such as liquid biopsy, treatments like immunotherapy, as well as deeper molecular knowledge; so, more options can be offered to patients with driver mutations. Groups with specific treatments account for around 25% and demonstrate significant increases in overall survival, and in some subgroups, it is important to evaluate each treatment alternative in accordance with scientific evidence, and even more so with immunotherapy. New treatments similarly mean that we must reconsider what should be done in oligometastatic disease where local treatment attains greater value.

Citing Articles

Peripheral Extracellular Vesicles for Diagnosis and Prognosis of Resectable Lung Cancer: The LUCEx Study Protocol.

Rodriguez-Sanz J, Munoz-Gonzalez N, Cubero J, Ordonez P, Gil V, Langarita R J Clin Med. 2025; 14(2).

PMID: 39860417 PMC: 11765880. DOI: 10.3390/jcm14020411.


A lung cancer diagnosis and treatment dataset with geno- and phenotypical characteristics of the patient.

Rios-Sanchez B, Vigueras G, Garcia A, Gomez-Bravo D, Menasalvas E, Torrente M Data Brief. 2024; 57:111167.

PMID: 39736907 PMC: 11683279. DOI: 10.1016/j.dib.2024.111167.


Explainable Machine Learning Predictions for the Benefit From Chemotherapy in Advanced Non-Small Cell Lung Cancer Without Available Targeted Mutations.

Shuang Z, Xingyu X, Yue C, Mingjing Y Clin Respir J. 2024; 18(12):e70044.

PMID: 39696772 PMC: 11655385. DOI: 10.1111/crj.70044.


Differentiation of pathological subtypes and Ki-67 and TTF-1 expression by dual-energy CT (DECT) volumetric quantitative analysis in non-small cell lung cancer.

Wu Y, Li J, Ding L, Huang J, Chen M, Li X Cancer Imaging. 2024; 24(1):146.

PMID: 39456114 PMC: 11515807. DOI: 10.1186/s40644-024-00793-6.


Management of oligometastatic and oligoprogressive epidermal growth factor receptor mutated non-small cell lung cancer patients: state of the art of a combined approach.

Di Pressa F, Perrone F, Benini A, Lohr F, Tiseo M, Bruni A Explor Target Antitumor Ther. 2024; 5(3):449-464.

PMID: 38966183 PMC: 11220311. DOI: 10.37349/etat.2024.00228.


References
1.
Videtic G, Donington J, Giuliani M, Heinzerling J, Karas T, Kelsey C . Stereotactic body radiation therapy for early-stage non-small cell lung cancer: Executive Summary of an ASTRO Evidence-Based Guideline. Pract Radiat Oncol. 2017; 7(5):295-301. DOI: 10.1016/j.prro.2017.04.014. View

2.
Lilenbaum R, Herndon 2nd J, List M, Desch C, Watson D, Miller A . Single-agent versus combination chemotherapy in advanced non-small-cell lung cancer: the cancer and leukemia group B (study 9730). J Clin Oncol. 2004; 23(1):190-6. DOI: 10.1200/JCO.2005.07.172. View

3.
Socinski M, Jotte R, Cappuzzo F, Orlandi F, Stroyakovskiy D, Nogami N . Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC. N Engl J Med. 2018; 378(24):2288-2301. DOI: 10.1056/NEJMoa1716948. View

4.
Li M, Zhang Q, Fu P, Li P, Peng A, Zhang G . Pemetrexed plus platinum as the first-line treatment option for advanced non-small cell lung cancer: a meta-analysis of randomized controlled trials. PLoS One. 2012; 7(5):e37229. PMC: 3355109. DOI: 10.1371/journal.pone.0037229. View

5.
Mok T, Cheng Y, Zhou X, Lee K, Nakagawa K, Niho S . Improvement in Overall Survival in a Randomized Study That Compared Dacomitinib With Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer and EGFR-Activating Mutations. J Clin Oncol. 2018; 36(22):2244-2250. DOI: 10.1200/JCO.2018.78.7994. View