Deciphering the Evolutionary Signatures of Pinnipeds Using Novel Genome Sequences: The First Genomes of Phoca Largha, Callorhinus Ursinus, and Eumetopias Jubatus

Overview

Journal Sci Rep

Specialty Science

Date 2018 Nov 17

PMID 30442995

Citations 5

Authors

Jung Youn Park

Kwondo Kim

Hawsun Sohn

Hyun Woo Kim

Yong-Rock An

Jung-Ha Kang

Eun-Mi Kim

Woori Kwak

Chul Lee

DongAhn Yoo

Jaehoon Jung

Samsun Sung

Joon Yoon

Heebal Kim

Affiliations

Soon will be listed here.

Abstract

The pinnipeds, which comprise seals, sea lions, and walruses, are a remarkable group of marine animals with unique adaptations to semi-aquatic life. However, their genomes are poorly characterized. In this study, we sequenced and characterized the genomes of three pinnipeds (Phoca largha, Callorhinus ursinus, and Eumetopias jubatus), focusing on site-wise sequence changes. We detected rapidly evolving genes in pinniped lineages and substitutions unique to pinnipeds associated with amphibious sound perception. Phenotypic convergence-related sequence convergences are not common in marine mammals. For example, FASN, KCNA5, and IL17RA contain substitutions specific to pinnipeds, yet are potential candidates of phenotypic convergence (blubber, response to hypoxia, and immunity to pathogens) in all marine mammals. The outcomes of this study will provide insight into targets for future studies of convergent evolution or gene function.

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