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Update on Global Epidemiology of Viral Hepatitis and Preventive Strategies

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Specialty General Medicine
Date 2018 Nov 16
PMID 30430114
Citations 125
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Abstract

Viral hepatitis is one of the major public health concerns around the world but until recently it has drawn little attention or funding from global health policymakers. Every year 1.4 million people die from viral hepatitis-related cirrhosis and liver cancer. However, the majority of the infected population are unaware of their condition. This population have significant obstacles to overcome such as lack of awareness, vulnerability, increased migration, disease stigma, discrimination, as well as poor health resources, conflict in policy development and program implementation. Despite implementing infection control measures over the last few decades eradication or significant disease reduction remains elusive. This study aims to present the current global prevalence status and examines potential elimination strategies. The information for this research were obtained through a systematic review, published scientific literatures, the official websites of various government organisations, international public health organisations and internationally recognised regulatory bodies over a period of 40 years between 1978 and 2018.

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References
1.
Mahajan R, Xing J, Liu S, Ly K, Moorman A, Rupp L . Mortality among persons in care with hepatitis C virus infection: the Chronic Hepatitis Cohort Study (CHeCS), 2006-2010. Clin Infect Dis. 2014; 58(8):1055-61. DOI: 10.1093/cid/ciu077. View

2.
Nelson P, Mathers B, Cowie B, Hagan H, Des Jarlais D, Horyniak D . Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews. Lancet. 2011; 378(9791):571-83. PMC: 3285467. DOI: 10.1016/S0140-6736(11)61097-0. View

3.
Heffernan A, Barber E, Cook N, Gomaa A, Harley Y, Jones C . Aiming at the Global Elimination of Viral Hepatitis: Challenges Along the Care Continuum. Open Forum Infect Dis. 2018; 5(1):ofx252. PMC: 5767952. DOI: 10.1093/ofid/ofx252. View

4.
Bruneau J, Zang G, Abrahamowicz M, Jutras-Aswad D, Daniel M, Roy E . Sustained drug use changes after hepatitis C screening and counseling among recently infected persons who inject drugs: a longitudinal study. Clin Infect Dis. 2013; 58(6):755-61. DOI: 10.1093/cid/cit938. View

5.
Sa-Nguanmoo P, Posuwan N, Vichaiwattana P, Wutthiratkowit N, Owatanapanich S, Wasitthankasem R . Swine is a possible source of hepatitis E virus infection by comparative study of hepatitis A and E seroprevalence in Thailand. PLoS One. 2015; 10(4):e0126184. PMC: 4415934. DOI: 10.1371/journal.pone.0126184. View