The Role of Statins in the Management of Patients Undergoing Coronary Artery Bypass Grafting

Overview

Journal Diseases

Date 2018 Nov 15

PMID 30423861

Citations 2

Authors

Dimitrios Siskos

Konstantinos Tziomalos

Affiliations

Soon will be listed here.

Abstract

Each year, a large number of patients undergo coronary artery bypass grafting surgery (CABG) worldwide. Accumulating evidence suggests that the preoperative administration of statins might be useful in preventing adverse events after CABG. In the present review, we discuss the role of statins in the perioperative management of patients undergoing CABG. Preoperative administration of statins in these patients substantially reduces the risk of postoperative atrial fibrillation and shortens hospital and intensive care unit (ICU) stay. Atorvastatin appears to be more effective, particularly when administered at high doses. Given these benefits and the safety of statins, their administration should be considered in patients undergoing CABG, even though the statins do not appear to affect the incidence of cardiovascular events and overall mortality perioperatively.

Citing Articles

Impact of perioperative high-intensity statin treatment on the occurrence of postoperative atrial fibrillation after coronary artery bypass grafting: a meta-analysis.

Lee Y, Im S, Kang Y, Sohn S, Jang M, Hwang H Acute Crit Care. 2024; 39(4):507-516.

PMID: 39600247 PMC: 11617835. DOI: 10.4266/acc.2024.00633.

Long-term mortality after isolated coronary artery bypass grafting and risk factors for mortality.

Chua T, Gao F, Chia S, Sin K, Naik M, Tan T J Cardiothorac Surg. 2024; 19(1):429.

PMID: 38987820 PMC: 11234617. DOI: 10.1186/s13019-024-02943-0.

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