Weaning from Mechanical Ventilation in ARDS: Aspects to Think About for Better Understanding, Evaluation, and Management

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2018 Nov 8

PMID 30402484

Citations 9

Authors

Iuri Christmann Wawrzeniak

Silvia Regina Rios Vieira

Josue Almeida Victorino

Affiliations

Soon will be listed here.

Abstract

Acute respiratory distress syndrome (ARDS) is characterized by severe inflammatory response and hypoxemia. The use of mechanical ventilation (MV) for correction of gas exchange can cause worsening of this inflammatory response, called "ventilator-induced lung injury" (VILI). The process of withdrawing mechanical ventilation, referred to as weaning from MV, may cause worsening of lung injury by spontaneous ventilation. Currently, there are few specific studies in patients with ARDS. Herein, we reviewed the main aspects of spontaneous ventilation and also discussed potential methods to predict the failure of weaning in this patient category. We also reviewed new treatments (modes of mechanical ventilation, neuromuscular blocker use, and extracorporeal membrane oxygenation) that could be considered in weaning ARDS patients from MV.

Citing Articles

Using Artificial Intelligence to Predict Mechanical Ventilation Weaning Success in Patients with Respiratory Failure, Including Those with Acute Respiratory Distress Syndrome.

Stivi T, Padawer D, Dirini N, Nachshon A, Batzofin B, Ledot S J Clin Med. 2024; 13(5).

PMID: 38592696 PMC: 10934889. DOI: 10.3390/jcm13051505.

Association between ventilator-associated events and implementation of acute respiratory distress syndrome (ARDS) ventilator weaning protocol.

Marshall G, Sanguinet J, Batra S, Foreman M, Peruchini J, Lopez S Am J Infect Control. 2023; 51(12):1321-1323.

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Regional peak flow as a novel approach to assess regional pulmonary mechanics by electrical impedance tomography: an observational validation study.

de Jongh S, Heines S, De Jongh F, Segers R, van der Horst I, van Bussel B Ann Transl Med. 2023; 11(6):253.

PMID: 37082694 PMC: 10113082. DOI: 10.21037/atm-22-3420.

Diaphragm Ultrasound: A Valuable Predictor of the Outcome of Extubation. An Observational Pilot Study in Covid-19 Related ARDS.

Gagliardi V, Butturini A, Ferraro G, Gagliardi G Arch Clin Biomed Res. 2023; 6(5):771-780.

PMID: 36643338 PMC: 9835007. DOI: 10.26502/acbr.50170290.

Transvenous Phrenic Nerve Stimulation in Patients Who Are Difficult to Wean.

Jha A Am J Respir Crit Care Med. 2022; 206(8):1047.

PMID: 35772121 PMC: 9801992. DOI: 10.1164/rccm.202206-1024LE.

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