Assessment of Health-Related Quality of Life in Pediatric Acute Lymphoblastic Leukemia Survivors: Perceptions of Children, Siblings, and Parents

Overview

Journal Turk J Haematol

Specialty Hematology

Date 2018 Nov 8

PMID 30401658

Citations 4

Authors

Deniz Kizmazoglu

Seher Sari

Melike Evim Sezgin

Arzu Kantarcioglu

Ozlem Tufekci

Fatma Demir Yenigurbuz

Birol Baytan

Sebnem Yilmaz

Adalet Meral Gunes

Hale Oren

Affiliations

Soon will be listed here.

Abstract

Objective: We investigated the health-related quality of life (HRQL) in survivors of pediatric acute lymphoblastic leukemia (ALL) and evaluated the perceptions of the children, their siblings, and their parents.

Materials And Methods: Seventy ALL survivors, who were between 7 and 17 years of age and had completed therapy ≥2 years, were included. The control group consisted of their healthy siblings. HRQL was assessed by the age-specific KINDL questionnaire.

Results: No significant differences could be found among HRQL scores of ALL survivors with respect to variables such as sex, risk group, and having chronic illness. HRQL scores for physical well-being, emotional well-being, family, and social functioning of the patient and sibling self-reports and parent proxy reports were lower than the expected values for healthy and chronically ill children.

Conclusion: These results demonstrate that both ALL survivors and their families need help via psychological counseling programs to improve their HRQL even after completion of therapy.

Citing Articles

Brothers and sisters of childhood acute leukemia survivors: Their long-term quality of life and its determinants.

Faust C, Auquier P, Hamidou Z, Bertrand Y, Tabone M, Ansoborlo S Cancer Med. 2022; 12(5):6200-6212.

PMID: 36266927 PMC: 10028038. DOI: 10.1002/cam4.5355.

Sociodemographic and Medical Determinants of Quality of Life in Long-Term Childhood Acute Lymphoblastic Leukemia Survivors Enrolled in EORTC CLG Studies.

Sleurs C, Musoro J, Rowsell A, Kicinski M, Suciu S, Chantziara S Cancers (Basel). 2022; 14(1).

PMID: 35008314 PMC: 8750449. DOI: 10.3390/cancers14010152.

Aili K, Arvidsson S, Nygren J Health Qual Life Outcomes. 2021; 19(1):55.

PMID: 33579311 PMC: 7881557. DOI: 10.1186/s12955-021-01700-4.

Identification of Evidence for Key Positive Psychological Constructs in Pediatric and Adolescent/Young Adult Patients with Cancer: A Scoping Review.

Wayant C, Manquen J, Wendelbo H, Kerr N, Crow M, Goodell J J Adolesc Young Adult Oncol. 2021; 10(3):247-259.

PMID: 33464990 PMC: 8220547. DOI: 10.1089/jayao.2020.0184.

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