Pneumonias in Adults Due to Mycoplasma, Chlamydiae, and Viruses

Overview

Journal Am J Med Sci

Publisher Elsevier

Specialty General Medicine

Date 1987 Jul 1

PMID 3037901

Authors

J P Luby

Affiliations

Soon will be listed here.

Abstract

Pneumonias in adults due to mycoplasma, chlamydiae, and viruses are a common clinical problem. These microorganisms contribute to the etiologies in 6-35% of all cases of pneumonia and are the sole pathogens in 1-17% of hospitalized cases. Important trends and developments in the field include the emergence of a Chlamydia psittaci strain (TWAR) that is passaged from human to human, causes a mycoplasma-like illness, and that is relatively resistant to erythromycin, the recognition of respiratory syncytial virus as a pathogen in nursing home outbreaks and in immunosuppressed adults, the continuing high lethality of fully developed influenza pneumonia, the efficacy of acyclovir and adenine arabinoside in limiting the complications of varicella-zoster virus infections, and the increasing frequency of pneumonia caused by cytomegalovirus and the severity of this disorder in highly immunosuppressed patients. Developments in the rapid diagnosis and therapy of respiratory syncytial virus infections with an aerosolized antiviral drug in children may pave the way for comparable advances in difficult pneumonias in adult patients.

References

Dean N . Mycoplasmal pneumonias in the community hospital. The "unusual" manifestations become common. Clin Chest Med. 1981; 2(1):121-31. View

Lehtomaki K, Julkunen I, Sandelin K, Salonen J, Virtanen M, Ranki M . Rapid diagnosis of respiratory adenovirus infections in young adult men. J Clin Microbiol. 1986; 24(1):108-11. PMC: 268842. DOI: 10.1128/jcm.24.1.108-111.1986. View

Shepp D, Dandliker P, Meyers J . Treatment of varicella-zoster virus infection in severely immunocompromised patients. A randomized comparison of acyclovir and vidarabine. N Engl J Med. 1986; 314(4):208-12. DOI: 10.1056/NEJM198601233140404. View

Meyer B, Stalder H, WEGMANN W . Persistent pulmonary granulomas after recovery from varicella pneumonia. Chest. 1986; 89(3):457-9. DOI: 10.1378/chest.89.3.457. View

Ramsey P, Fife K, Hackman R, Meyers J, Corey L . Herpes simplex virus pneumonia: clinical, virologic, and pathologic features in 20 patients. Ann Intern Med. 1982; 97(6):813-20. DOI: 10.7326/0003-4819-97-6-813. View

Reimann H . Landmark article Dec 24,1938: An acute infection of the respiratory tract with atypical pneumonia. A disease entity probably caused by a filtrable virus. By Hobart A. Reimann. JAMA. 1984; 251(7):936-44. View

Saikku P, Wang S, Kleemola M, BRANDER E, Rusanen E, GRAYSTON J . An epidemic of mild pneumonia due to an unusual strain of Chlamydia psittaci. J Infect Dis. 1985; 151(5):832-9. DOI: 10.1093/infdis/151.5.832. View

Luby J, Ware A, HULL A, Helderman J, Gailiunas P, Butler S . Disease due to cytomegalovirus and its long-term consequences in renal transplant recipients. Correlation of allograft survival with disease due to cytomegalovirus and rubella antibody level. Arch Intern Med. 1983; 143(6):1126-9. View

Granato P, Poe L, Weiner L . New York City medium for enhanced recovery of Mycoplasma pneumoniae from clinical specimens. J Clin Microbiol. 1983; 17(6):1077-80. PMC: 272805. DOI: 10.1128/jcm.17.6.1077-1080.1983. View

10.

Macfarlane J, Miller A, Roderick Smith W, Morris A, Rose D . Comparative radiographic features of community acquired Legionnaires' disease, pneumococcal pneumonia, mycoplasma pneumonia, and psittacosis. Thorax. 1984; 39(1):28-33. PMC: 459717. DOI: 10.1136/thx.39.1.28. View

11.

Foy H, COONEY M, McMahan R, GRAYSTON J . Viral and mycoplasmal pneumonia in a prepaid medical care group during an eight-year period. Am J Epidemiol. 1973; 97(2):93-102. DOI: 10.1093/oxfordjournals.aje.a121493. View

12.

FRANCIS Jr T . Influenza: the new acquayantance. Ann Intern Med. 1953; 39(2):203-21. DOI: 10.7326/0003-4819-39-2-203. View

13.

Izumikawa K, Hara K . Clinical features of mycoplasmal pneumonia in adults. Yale J Biol Med. 1983; 56(5-6):505-10. PMC: 2590534. View

14.

Myerowitz R, Stalder H, Oxman M, Levin M, Moore M, Leith J . Fatal disseminated adenovirus infection in a renal transplant recipient. Am J Med. 1975; 59(4):591-8. DOI: 10.1016/0002-9343(75)90267-3. View

15.

Berntsson E, Blomberg J, Lagergard T, Trollfors B . Etiology of community-acquired pneumonia in patients requiring hospitalization. Eur J Clin Microbiol. 1985; 4(3):268-72. DOI: 10.1007/BF02013650. View

16.

Kuritsky J, Schmid G, Potter M, Anderson D, Kaufmann A . Psittacosis. A diagnostic challenge. J Occup Med. 1984; 26(10):731-3. View

17.

Edelman R, Hann L, Simon M . Chlamydia trachomatis pneumonia in adults: radiographic appearance. Radiology. 1984; 152(2):279-82. DOI: 10.1148/radiology.152.2.6739784. View

18.

Shields A, Hackman R, Fife K, Corey L, Meyers J . Adenovirus infections in patients undergoing bone-marrow transplantation. N Engl J Med. 1985; 312(9):529-33. DOI: 10.1056/NEJM198502283120901. View

19.

Cockcroft D, Stilwell G . Lobar pneumonia caused by Mycoplasma pneumoniae. Can Med Assoc J. 1981; 124(11):1463-8. PMC: 1862327. View

20.

Ponka A, Sarna S . Differential diagnosis of viral, mycoplasmal and bacteraemic pneumococcal pneumonias on admission to hospital. Eur J Respir Dis. 1983; 64(5):360-8. View